Staining pattern of specific and cross‐reacting Melan‐A antibodies: A comparative study on 15,840 samples from 133 human tumor types

The Melan‐A (melanocyte antigen) protein, also termed ‘melanoma antigen recognized by T cells 1’ (MART‐1) is a protein with unknown function whose expression is specific for the melanocyte lineage. Antibodies against Melan‐A are thus used for identifying melanocytic tumors, but some Melan‐A antibodi...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2024-07, Vol.132 (7), p.479-491
Hauptverfasser:	Boroojerdi, Shiva, Weidemann, Sören, Menz, Anne, Lennartz, Maximilian, Dwertmann Rico, Sebastian, Schlichter, Ria, Kind, Simon, Reiswich, Viktor, Viehweger, Florian, Bawahab, Ahmed Abdulwahab, Höflmeyer, Doris, Fraune, Christoph, Gorbokon, Natalia, Luebke, Andreas M., Hube‐Magg, Claudia, Büscheck, Franziska, Krech, Till, Hinsch, Andrea, Jacobsen, Frank, Burandt, Eike, Sauter, Guido, Simon, Ronald, Kluth, Martina, Steurer, Stefan, Minner, Sarah, Marx, Andreas H., Bernreuther, Christian, Clauditz, Till S., Dum, David, Lebok, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Biomarkers, Tumor - analysis Biomarkers, Tumor - immunology Comparative studies Cross Reactions - immunology Cross‐reactive antibody diagnostic Female Humans Immunohistochemistry Immunohistochemistry - methods Lymphocytes Lymphocytes T MART-1 Antigen - analysis MART-1 Antigen - immunology Melanoma Melanoma - diagnosis Melanoma - immunology Melanoma - pathology Melan‐A Metastases Neoplasms Neoplasms - diagnosis Neoplasms - immunology Neoplasms - pathology Proteins Staining Stroma Tissue Array Analysis tissue microarray Tumors Urothelial carcinoma
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