Liposomes-Encapsulating Double-Stranded Nucleic Acid (Poly I:C) for Head and Neck Cancer Treatment

Polyriboinosinic acid–polyribocytidylic acid (Poly I:C) serves as a synthetic mimic of viral double-stranded dsRNA, capable of inducing apoptosis in numerous cancer cells. Despite its potential, therapeutic benefits, the application of Poly I:C has been hindered by concerns regarding toxicity, stabi...

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Veröffentlicht in:ACS pharmacology & translational science 2024-05, Vol.7 (5), p.1612-1623
Hauptverfasser: Singh, Vidit, Chernatynskaya, Anna, Qi, Lin, Chuang, Hsin-Yin, Cole, Tristan, Jeyalatha, Vimalin Mani, Bhargava, Lavanya, Yeudall, W. Andrew, Farkas, Laszlo, Yang, Hu
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Sprache:eng
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