Risk assessments of drug-related problems for cardiac surgery patients
Patients undergoing cardiac surgery are considered at high risk for developing drug-related problems (DRPs) due to comorbidities and complexity of drug treatment. This study aimed to identify DRPs in patients undergoing cardiac surgery and to develop and implement a framework to reduce potential ris...
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| Veröffentlicht in: | The American journal of managed care 2024-05, Vol.30 (5), p.e140-e146 |
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| container_title | The American journal of managed care |
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| creator | Kelleci Çakır, Burcu Kaşıkcı, Merve Aydın, Ahmet Yılmaz, Mustafa Bayraktar-Ekincioglu, Aygin |
| description | Patients undergoing cardiac surgery are considered at high risk for developing drug-related problems (DRPs) due to comorbidities and complexity of drug treatment. This study aimed to identify DRPs in patients undergoing cardiac surgery and to develop and implement a framework to reduce potential risks associated with drug treatment.
Prospectively designed quasi-experimental study.
This study consisted of observational (risk assessment and framework development) and interventional (framework implementation) periods and was conducted at a department of cardiovascular surgery in a university hospital. An expert panel evaluated the causes of DRPs. Then a framework was developed in consensus to identify safeguards to be implemented during the interventional period.
A total of 200 patients (100 patients per study period) were included. During the observational period, a total of 275 DRPs and 487 causes were identified; 74.5% of DRPs were not solved. For the risk analysis, 487 causes were evaluated and only 32.6% were considered acceptable risk. By implementing the framework in the interventional period, 215 DRPs and 304 causes were identified and 386 interventions were recommended by a clinical pharmacist. A total of 342 (88.6%) interventions were accepted by a health care team, and 128 (59.5%) DRPs were completely solved. For the risk analysis, 304 causes were evaluated and 84.9% were considered acceptable risk ( P |
| doi_str_mv | 10.37765/ajmc.2024.89541 |
| format | Article |
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Prospectively designed quasi-experimental study.
This study consisted of observational (risk assessment and framework development) and interventional (framework implementation) periods and was conducted at a department of cardiovascular surgery in a university hospital. An expert panel evaluated the causes of DRPs. Then a framework was developed in consensus to identify safeguards to be implemented during the interventional period.
A total of 200 patients (100 patients per study period) were included. During the observational period, a total of 275 DRPs and 487 causes were identified; 74.5% of DRPs were not solved. For the risk analysis, 487 causes were evaluated and only 32.6% were considered acceptable risk. By implementing the framework in the interventional period, 215 DRPs and 304 causes were identified and 386 interventions were recommended by a clinical pharmacist. A total of 342 (88.6%) interventions were accepted by a health care team, and 128 (59.5%) DRPs were completely solved. For the risk analysis, 304 causes were evaluated and 84.9% were considered acceptable risk ( P < .001 compared with the observational period).
It is possible to reduce risk levels or prevent occurrence of DRPs by implementing a framework for risk management developed by a multidisciplinary care team in areas such as cardiac surgery where time is limited.</description><identifier>ISSN: 1088-0224</identifier><identifier>ISSN: 1936-2692</identifier><identifier>EISSN: 1936-2692</identifier><identifier>DOI: 10.37765/ajmc.2024.89541</identifier><identifier>PMID: 38748914</identifier><language>eng</language><publisher>United States: MultiMedia Healthcare Inc</publisher><subject>Aged ; Cardiac Surgical Procedures - adverse effects ; Drug therapy ; Drug-Related Side Effects and Adverse Reactions - prevention & control ; Female ; Heart surgery ; Hospitals ; Humans ; Male ; Medical errors ; Middle Aged ; Patient safety ; Pharmacists ; Polypharmacy ; Prospective Studies ; Risk Assessment</subject><ispartof>The American journal of managed care, 2024-05, Vol.30 (5), p.e140-e146</ispartof><rights>Copyright MultiMedia Healthcare Inc. 2024</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/3053422310?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,12745,12774,21388,21389,21390,21391,21392,23256,27924,27925,33452,33453,33530,33531,33703,33704,33744,33745,34005,34006,34314,34315,34334,34335,36265,36266,43616,43659,43787,43805,43953,44067,44073,44404,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38748914$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kelleci Çakır, Burcu</creatorcontrib><creatorcontrib>Kaşıkcı, Merve</creatorcontrib><creatorcontrib>Aydın, Ahmet</creatorcontrib><creatorcontrib>Yılmaz, Mustafa</creatorcontrib><creatorcontrib>Bayraktar-Ekincioglu, Aygin</creatorcontrib><title>Risk assessments of drug-related problems for cardiac surgery patients</title><title>The American journal of managed care</title><addtitle>Am J Manag Care</addtitle><description>Patients undergoing cardiac surgery are considered at high risk for developing drug-related problems (DRPs) due to comorbidities and complexity of drug treatment. This study aimed to identify DRPs in patients undergoing cardiac surgery and to develop and implement a framework to reduce potential risks associated with drug treatment.
Prospectively designed quasi-experimental study.
This study consisted of observational (risk assessment and framework development) and interventional (framework implementation) periods and was conducted at a department of cardiovascular surgery in a university hospital. An expert panel evaluated the causes of DRPs. Then a framework was developed in consensus to identify safeguards to be implemented during the interventional period.
A total of 200 patients (100 patients per study period) were included. During the observational period, a total of 275 DRPs and 487 causes were identified; 74.5% of DRPs were not solved. For the risk analysis, 487 causes were evaluated and only 32.6% were considered acceptable risk. By implementing the framework in the interventional period, 215 DRPs and 304 causes were identified and 386 interventions were recommended by a clinical pharmacist. A total of 342 (88.6%) interventions were accepted by a health care team, and 128 (59.5%) DRPs were completely solved. For the risk analysis, 304 causes were evaluated and 84.9% were considered acceptable risk ( P < .001 compared with the observational period).
It is possible to reduce risk levels or prevent occurrence of DRPs by implementing a framework for risk management developed by a multidisciplinary care team in areas such as cardiac surgery where time is limited.</description><subject>Aged</subject><subject>Cardiac Surgical Procedures - adverse effects</subject><subject>Drug therapy</subject><subject>Drug-Related Side Effects and Adverse Reactions - prevention & control</subject><subject>Female</subject><subject>Heart surgery</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Male</subject><subject>Medical errors</subject><subject>Middle Aged</subject><subject>Patient safety</subject><subject>Pharmacists</subject><subject>Polypharmacy</subject><subject>Prospective Studies</subject><subject>Risk Assessment</subject><issn>1088-0224</issn><issn>1936-2692</issn><issn>1936-2692</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkD1PwzAURS0EoqWwMyFLLCwp9vNHnBFVFJAqISGYLcexq5SkKXYy9N_jtMDA9N5w7tXVQeiakjnLcynuzaa1cyDA56oQnJ6gKS2YzEAWcJp-olRGAPgEXcS4IYRJxeU5mjCVc1VQPkXLtzp-YhOji7F12z7izuMqDOssuMb0rsK70JWNayP2XcDWhKo2FschrF3Y453p6zF1ic68aaK7-rkz9LF8fF88Z6vXp5fFwyqzoEifqZIZywVnXjrlKfGkpJ5a4J5Tr4T1ObOGUW4ZeEj7PAGhhATLC6eKUrIZujv2plVfg4u9butoXdOYreuGqBkRIpkAUAm9_YduuiFs07qRYhyAUZIocqRs6GIMzutdqFsT9poSfXCsR8d6dKwPjlPk5qd4KFtX_QV-pbJv2dV3Fw</recordid><startdate>20240501</startdate><enddate>20240501</enddate><creator>Kelleci Çakır, Burcu</creator><creator>Kaşıkcı, Merve</creator><creator>Aydın, Ahmet</creator><creator>Yılmaz, Mustafa</creator><creator>Bayraktar-Ekincioglu, Aygin</creator><general>MultiMedia Healthcare Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88C</scope><scope>88M</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>KB0</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M0T</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20240501</creationdate><title>Risk assessments of drug-related problems for cardiac surgery patients</title><author>Kelleci Çakır, Burcu ; Kaşıkcı, Merve ; Aydın, Ahmet ; Yılmaz, Mustafa ; Bayraktar-Ekincioglu, Aygin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c280t-8b3ac4543f6e8f10f0b1f1c24f41f85cf73ca314c32f2914f0258562c49e89b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Aged</topic><topic>Cardiac Surgical Procedures - adverse effects</topic><topic>Drug therapy</topic><topic>Drug-Related Side Effects and Adverse Reactions - prevention & control</topic><topic>Female</topic><topic>Heart surgery</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Male</topic><topic>Medical errors</topic><topic>Middle Aged</topic><topic>Patient safety</topic><topic>Pharmacists</topic><topic>Polypharmacy</topic><topic>Prospective Studies</topic><topic>Risk Assessment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kelleci Çakır, Burcu</creatorcontrib><creatorcontrib>Kaşıkcı, Merve</creatorcontrib><creatorcontrib>Aydın, Ahmet</creatorcontrib><creatorcontrib>Yılmaz, Mustafa</creatorcontrib><creatorcontrib>Bayraktar-Ekincioglu, Aygin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Access via ABI/INFORM (ProQuest)</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>ABI/INFORM Complete - 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Academic</collection><jtitle>The American journal of managed care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kelleci Çakır, Burcu</au><au>Kaşıkcı, Merve</au><au>Aydın, Ahmet</au><au>Yılmaz, Mustafa</au><au>Bayraktar-Ekincioglu, Aygin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk assessments of drug-related problems for cardiac surgery patients</atitle><jtitle>The American journal of managed care</jtitle><addtitle>Am J Manag Care</addtitle><date>2024-05-01</date><risdate>2024</risdate><volume>30</volume><issue>5</issue><spage>e140</spage><epage>e146</epage><pages>e140-e146</pages><issn>1088-0224</issn><issn>1936-2692</issn><eissn>1936-2692</eissn><abstract>Patients undergoing cardiac surgery are considered at high risk for developing drug-related problems (DRPs) due to comorbidities and complexity of drug treatment. This study aimed to identify DRPs in patients undergoing cardiac surgery and to develop and implement a framework to reduce potential risks associated with drug treatment.
Prospectively designed quasi-experimental study.
This study consisted of observational (risk assessment and framework development) and interventional (framework implementation) periods and was conducted at a department of cardiovascular surgery in a university hospital. An expert panel evaluated the causes of DRPs. Then a framework was developed in consensus to identify safeguards to be implemented during the interventional period.
A total of 200 patients (100 patients per study period) were included. During the observational period, a total of 275 DRPs and 487 causes were identified; 74.5% of DRPs were not solved. For the risk analysis, 487 causes were evaluated and only 32.6% were considered acceptable risk. By implementing the framework in the interventional period, 215 DRPs and 304 causes were identified and 386 interventions were recommended by a clinical pharmacist. A total of 342 (88.6%) interventions were accepted by a health care team, and 128 (59.5%) DRPs were completely solved. For the risk analysis, 304 causes were evaluated and 84.9% were considered acceptable risk ( P < .001 compared with the observational period).
It is possible to reduce risk levels or prevent occurrence of DRPs by implementing a framework for risk management developed by a multidisciplinary care team in areas such as cardiac surgery where time is limited.</abstract><cop>United States</cop><pub>MultiMedia Healthcare Inc</pub><pmid>38748914</pmid><doi>10.37765/ajmc.2024.89541</doi></addata></record> |
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| subjects | Aged Cardiac Surgical Procedures - adverse effects Drug therapy Drug-Related Side Effects and Adverse Reactions - prevention & control Female Heart surgery Hospitals Humans Male Medical errors Middle Aged Patient safety Pharmacists Polypharmacy Prospective Studies Risk Assessment |
| title | Risk assessments of drug-related problems for cardiac surgery patients |
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