Iridium-catalyzed reductive β-alkylation of (iso)quinoline derivatives by an in situ enone-trapping strategy

By employing [IrCp*Cl ] /Mg(OMe) /(CH O) as an applicable catalyst system, we report a reductive β-alkylation of (iso)quinolinium salts with cost-effective and readily available β-chloro ketones, proceeding with good chemoselectivity, mild reaction conditions, and without the need for introduction o...

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Veröffentlicht in:	Organic & biomolecular chemistry 2024-06, Vol.22 (22), p.4516-4520
Hauptverfasser:	Sun, Yanping, Chen, Jianjie, Zhang, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Adducts Alkylation Catalysts Hydrides Iridium Ketones Quinoline Trapping
Online-Zugang:	Volltext
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