Downregulation of SPARC Expression Enhances the Fusion of BeWo Choriocarcinoma Cells

Syncytiotrophoblasts, which are formed by the fusion of villous cytotrophoblasts, play an essential role in maintaining a successful pregnancy. Secreted protein acidic and rich in cysteine (SPARC) is a non-structural Ca 2+ -binding extracellular matrix glycoprotein involved in tissue remodeling and...

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Veröffentlicht in:	Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2024-08, Vol.31 (8), p.2342-2353
Hauptverfasser:	Togo, Atsuko, Mitsuzuka, Kanako, Hanawa, Sachiko, Nakajima, Rie, Izumi, Kenji, Sato, Kenji, Ishimoto, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation Cell Fusion Cell Line, Tumor Choriocarcinoma - genetics Choriocarcinoma - metabolism Choriocarcinoma - pathology Down-Regulation Embryology Female Humans Medicine Medicine & Public Health Obstetrics/Perinatology/Midwifery Osteonectin - genetics Osteonectin - metabolism Placenta - metabolism Pregnancy Pregnancy: Original Article Reproductive Medicine Trophoblasts - metabolism
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