Insights into posttranslational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP

Mice with skeletal muscle-specific and inducible double knockout of the lysine acetyltransferases, p300 (E1A binding protein p300) and CBP (cAMP-response element-binding protein binding protein), referred to as i-mPCKO, demonstrate a dramatic loss of contractile function in skeletal muscle and ultim...

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Veröffentlicht in:	Journal of applied physiology (1985) 2024-06, Vol.136 (6), p.1559
Hauptverfasser:	Meyer, Gretchen A, Ferey, Jeremie L A, Sanford, James A, Fitzgerald, Liam S, Greenberg, Akiva E, Svensson, Kristoffer, Greenberg, Michael J, Schenk, Simon
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Actin Actomyosin Adenosine Triphosphate - metabolism Animals Ankle ATP Calcium - metabolism Calcium ions CREB-Binding Protein - metabolism Cycles E1A-Associated p300 Protein - metabolism Electron transport Genotypes Lysine Male Mice Mice, Knockout Mitochondria Muscle contraction Muscle Contraction - physiology Muscle, Skeletal - metabolism Muscle, Skeletal - physiology Muscles Musculoskeletal system Myosin Protein Processing, Post-Translational Proteins Proteomes Respiratory function Skeletal muscle
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