Ultrasound-Guided Hip Injections with High Density Hyaluronic Acid: Outcome at One Year Follow Up
: The ultrasound-guided viscosupplementation of the hip joint with hyaluronic acid (HA) is considered a standard procedure among the conservative treatments for hip arthritis. The aim of this study was to evaluate the clinical benefit and the incidence of adverse events of the technique in an observ...
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Veröffentlicht in: | Journal of clinical medicine 2024-05, Vol.13 (9), p.2515 |
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description | : The ultrasound-guided viscosupplementation of the hip joint with hyaluronic acid (HA) is considered a standard procedure among the conservative treatments for hip arthritis. The aim of this study was to evaluate the clinical benefit and the incidence of adverse events of the technique in an observational study at one year follow up.
We evaluated a consecutive series of 85 patients with a diagnosis of symptomatic arthritis who underwent intra-articular ultrasound-guided hyaluronic acid injections. The scales used for evaluation were modified Harris Hip Score (mHHS), WOMAC (Western Ontario and McMaster University), and Hip Outcome Score (HOS) with subscale Sport (HOSs), for pain the Visual Analogic Scale (VAS). The patients were classified according to Tonnis' radiological classification of arthritis (range 0-3): 20 patients (grade 0), 32 (grade 1), 18 (grade 2), 15 (grade 3).
At last follow up, all the scales increased: mHHS from 59.35 to 82.1, HOS from 69.45 to 78.53, HOss from 47.4 to 58.11, VAS from 6.09 to 3.97, WOMAC from 33.2 to 31.5 (
< 0.05 for all the parameters); the results were elaborated with GraphPad Prism v5.0 (Prism Software La Jolla, CA, USA) using Wilcoxon's test. A total of 13 patients out of 85 needed arthroplasty, all classified as Tonnis grade 3. No serious adverse events were noted due to the procedure.
Based on our findings, indication for the use of hyaluronic acid is limited to patients with mild to moderate arthritis. Patients in advanced arthritis refusing replacement surgery and asking for this treatment should be informed about the poor results of the technique even in the short term. |
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We evaluated a consecutive series of 85 patients with a diagnosis of symptomatic arthritis who underwent intra-articular ultrasound-guided hyaluronic acid injections. The scales used for evaluation were modified Harris Hip Score (mHHS), WOMAC (Western Ontario and McMaster University), and Hip Outcome Score (HOS) with subscale Sport (HOSs), for pain the Visual Analogic Scale (VAS). The patients were classified according to Tonnis' radiological classification of arthritis (range 0-3): 20 patients (grade 0), 32 (grade 1), 18 (grade 2), 15 (grade 3).
At last follow up, all the scales increased: mHHS from 59.35 to 82.1, HOS from 69.45 to 78.53, HOss from 47.4 to 58.11, VAS from 6.09 to 3.97, WOMAC from 33.2 to 31.5 (
< 0.05 for all the parameters); the results were elaborated with GraphPad Prism v5.0 (Prism Software La Jolla, CA, USA) using Wilcoxon's test. A total of 13 patients out of 85 needed arthroplasty, all classified as Tonnis grade 3. No serious adverse events were noted due to the procedure.
Based on our findings, indication for the use of hyaluronic acid is limited to patients with mild to moderate arthritis. Patients in advanced arthritis refusing replacement surgery and asking for this treatment should be informed about the poor results of the technique even in the short term.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm13092515</identifier><identifier>PMID: 38731044</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Antiarthritic agents ; Arthritis ; Care and treatment ; Harris, W.H ; Hip joint ; Hyaluronic acid ; Infections ; Injections, Intra-articular ; Orthopedics ; Osteoarthritis ; Pain ; Patients ; Steroids ; Surgery ; Ultrasonic imaging ; Ultrasound imaging</subject><ispartof>Journal of clinical medicine, 2024-05, Vol.13 (9), p.2515</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c379t-216c3068fdeddcc5b896ed70695ecd5b6762deeeeb92e4b5846675224929c7af3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27931,27932</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38731044$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Battaglia, Antonino Giulio</creatorcontrib><creatorcontrib>D'Apolito, Rocco</creatorcontrib><creatorcontrib>Labionda, Fabio</creatorcontrib><creatorcontrib>Ramazzotti, Joil</creatorcontrib><creatorcontrib>Zagra, Luigi</creatorcontrib><title>Ultrasound-Guided Hip Injections with High Density Hyaluronic Acid: Outcome at One Year Follow Up</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>: The ultrasound-guided viscosupplementation of the hip joint with hyaluronic acid (HA) is considered a standard procedure among the conservative treatments for hip arthritis. The aim of this study was to evaluate the clinical benefit and the incidence of adverse events of the technique in an observational study at one year follow up.
We evaluated a consecutive series of 85 patients with a diagnosis of symptomatic arthritis who underwent intra-articular ultrasound-guided hyaluronic acid injections. The scales used for evaluation were modified Harris Hip Score (mHHS), WOMAC (Western Ontario and McMaster University), and Hip Outcome Score (HOS) with subscale Sport (HOSs), for pain the Visual Analogic Scale (VAS). The patients were classified according to Tonnis' radiological classification of arthritis (range 0-3): 20 patients (grade 0), 32 (grade 1), 18 (grade 2), 15 (grade 3).
At last follow up, all the scales increased: mHHS from 59.35 to 82.1, HOS from 69.45 to 78.53, HOss from 47.4 to 58.11, VAS from 6.09 to 3.97, WOMAC from 33.2 to 31.5 (
< 0.05 for all the parameters); the results were elaborated with GraphPad Prism v5.0 (Prism Software La Jolla, CA, USA) using Wilcoxon's test. A total of 13 patients out of 85 needed arthroplasty, all classified as Tonnis grade 3. No serious adverse events were noted due to the procedure.
Based on our findings, indication for the use of hyaluronic acid is limited to patients with mild to moderate arthritis. Patients in advanced arthritis refusing replacement surgery and asking for this treatment should be informed about the poor results of the technique even in the short term.</description><subject>Antiarthritic agents</subject><subject>Arthritis</subject><subject>Care and treatment</subject><subject>Harris, W.H</subject><subject>Hip joint</subject><subject>Hyaluronic acid</subject><subject>Infections</subject><subject>Injections, Intra-articular</subject><subject>Orthopedics</subject><subject>Osteoarthritis</subject><subject>Pain</subject><subject>Patients</subject><subject>Steroids</subject><subject>Surgery</subject><subject>Ultrasonic imaging</subject><subject>Ultrasound imaging</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkc9rFTEQx4MottSevEvAiyBb8zsbb49q-wqFd_EdPC3ZZLbNYzd5JruU9983tVWrOHOYYfjM8GW-CL2l5IxzQz7t3EQ5MUxS-QIdM6J1Q3jLXz7rj9BpKTtSo20Fo_o1OuKt5pQIcYzsdpyzLWmJvrlcggeP12GPr-IO3BxSLPguzLd1dnOLv0AsYT7g9cGOS04xOLxywX_Gm2V2aQJsZ7yJgL-DzfgijWO6w9v9G_RqsGOB06d6grYXX7-dr5vrzeXV-eq6cVybuWFUOU5UO1QJ3jnZt0aB10QZCc7LXmnFPNToDQPRy1YopSVjwjDjtB34CfrweHef048FytxNoTgYRxshLaXjRHKjW8FpRd__g-7SkmNV95OiQhFG_lA3doQuxCHVT7mHo91KGy6VMFpW6uw_VE0PU3ApwhDq_K-Fj48LLqdSMgzdPofJ5kNHSffgaffM00q_e5K69BP43-wvB_k9GMaZUg</recordid><startdate>20240501</startdate><enddate>20240501</enddate><creator>Battaglia, Antonino Giulio</creator><creator>D'Apolito, Rocco</creator><creator>Labionda, Fabio</creator><creator>Ramazzotti, Joil</creator><creator>Zagra, Luigi</creator><general>MDPI AG</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20240501</creationdate><title>Ultrasound-Guided Hip Injections with High Density Hyaluronic Acid: Outcome at One Year Follow Up</title><author>Battaglia, Antonino Giulio ; D'Apolito, Rocco ; Labionda, Fabio ; Ramazzotti, Joil ; Zagra, Luigi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c379t-216c3068fdeddcc5b896ed70695ecd5b6762deeeeb92e4b5846675224929c7af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Antiarthritic agents</topic><topic>Arthritis</topic><topic>Care and treatment</topic><topic>Harris, W.H</topic><topic>Hip joint</topic><topic>Hyaluronic acid</topic><topic>Infections</topic><topic>Injections, Intra-articular</topic><topic>Orthopedics</topic><topic>Osteoarthritis</topic><topic>Pain</topic><topic>Patients</topic><topic>Steroids</topic><topic>Surgery</topic><topic>Ultrasonic imaging</topic><topic>Ultrasound imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Battaglia, Antonino Giulio</creatorcontrib><creatorcontrib>D'Apolito, Rocco</creatorcontrib><creatorcontrib>Labionda, Fabio</creatorcontrib><creatorcontrib>Ramazzotti, Joil</creatorcontrib><creatorcontrib>Zagra, Luigi</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Battaglia, Antonino Giulio</au><au>D'Apolito, Rocco</au><au>Labionda, Fabio</au><au>Ramazzotti, Joil</au><au>Zagra, Luigi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ultrasound-Guided Hip Injections with High Density Hyaluronic Acid: Outcome at One Year Follow Up</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2024-05-01</date><risdate>2024</risdate><volume>13</volume><issue>9</issue><spage>2515</spage><pages>2515-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>: The ultrasound-guided viscosupplementation of the hip joint with hyaluronic acid (HA) is considered a standard procedure among the conservative treatments for hip arthritis. The aim of this study was to evaluate the clinical benefit and the incidence of adverse events of the technique in an observational study at one year follow up.
We evaluated a consecutive series of 85 patients with a diagnosis of symptomatic arthritis who underwent intra-articular ultrasound-guided hyaluronic acid injections. The scales used for evaluation were modified Harris Hip Score (mHHS), WOMAC (Western Ontario and McMaster University), and Hip Outcome Score (HOS) with subscale Sport (HOSs), for pain the Visual Analogic Scale (VAS). The patients were classified according to Tonnis' radiological classification of arthritis (range 0-3): 20 patients (grade 0), 32 (grade 1), 18 (grade 2), 15 (grade 3).
At last follow up, all the scales increased: mHHS from 59.35 to 82.1, HOS from 69.45 to 78.53, HOss from 47.4 to 58.11, VAS from 6.09 to 3.97, WOMAC from 33.2 to 31.5 (
< 0.05 for all the parameters); the results were elaborated with GraphPad Prism v5.0 (Prism Software La Jolla, CA, USA) using Wilcoxon's test. A total of 13 patients out of 85 needed arthroplasty, all classified as Tonnis grade 3. No serious adverse events were noted due to the procedure.
Based on our findings, indication for the use of hyaluronic acid is limited to patients with mild to moderate arthritis. Patients in advanced arthritis refusing replacement surgery and asking for this treatment should be informed about the poor results of the technique even in the short term.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>38731044</pmid><doi>10.3390/jcm13092515</doi><oa>free_for_read</oa></addata></record> |
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subjects | Antiarthritic agents Arthritis Care and treatment Harris, W.H Hip joint Hyaluronic acid Infections Injections, Intra-articular Orthopedics Osteoarthritis Pain Patients Steroids Surgery Ultrasonic imaging Ultrasound imaging |
title | Ultrasound-Guided Hip Injections with High Density Hyaluronic Acid: Outcome at One Year Follow Up |
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