The Role of One-Carbon Metabolism and Methyl Donors in Medically Assisted Reproduction: A Narrative Review of the Literature

One-carbon (1-C) metabolic deficiency impairs homeostasis, driving disease development, including infertility. It is of importance to summarize the current evidence regarding the clinical utility of 1-C metabolism-related biomolecules and methyl donors, namely, folate, betaine, choline, vitamin B12,...

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Veröffentlicht in:	International journal of molecular sciences 2024-05, Vol.25 (9), p.4977
Hauptverfasser:	Sfakianoudis, Konstantinos, Zikopoulos, Athanasios, Grigoriadis, Sokratis, Seretis, Nikolaos, Maziotis, Evangelos, Anifandis, George, Xystra, Paraskevi, Kostoulas, Charilaos, Giougli, Urania, Pantos, Konstantinos, Simopoulou, Mara, Georgiou, Ioannis
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Betaine - metabolism Biomarkers Carbon - metabolism Choline Choline - metabolism Dietary Supplements Epigenetic inheritance Female Fertilization in Vitro - methods Folic acid Folic Acid - metabolism Homocysteine Homocysteine - blood Homocysteine - metabolism Humans Infertility Metabolites Reproductive Techniques, Assisted Vitamin B 12 - metabolism Zinc - metabolism Zinc in the body
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