Therapeutic drug monitoring in pregnancy: Levetiracetam

Objective Levetiracetam (LEV) is an antiseizure medication that is mainly excreted by the kidneys. Due to its low teratogenic risk, LEV is frequently prescribed for women with epilepsy (WWE). Physiological changes during gestation affect the pharmacokinetic characteristics of LEV. The goal of our st...

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Veröffentlicht in:	Epilepsia (Copenhagen) 2024-05, Vol.65 (5), p.1285-1293
Hauptverfasser:	Fallik, Noam, Trakhtenbroit, Ilia, Fahoum, Firas, Goldstein, Lilach
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anticonvulsants - administration & dosage Anticonvulsants - blood Anticonvulsants - pharmacokinetics Anticonvulsants - therapeutic use blood level Blood levels clearance Convulsions & seizures Dosage Drug Monitoring - methods Epilepsy Epilepsy - blood Epilepsy - drug therapy Etiracetam Female Gestation Humans levetiracetam Levetiracetam - administration & dosage Levetiracetam - blood Levetiracetam - pharmacokinetics Levetiracetam - therapeutic use Patients Pharmacokinetics Postpartum Postpartum Period Pregnancy Pregnancy Complications - blood Pregnancy Complications - drug therapy Retrospective Studies Seizures Serum levels Teratogenicity therapeutic drug monitoring Toxicity Womens health Young Adult
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