The impact of bladder problems on well-being in multiple sclerosis – A cross-sectional study

•Bladder problems affect well-being in patients with multiple sclerosis.•Patients report wanting help with bladder management, emphasizing an unmet need.•Attempting self-management instead of receiving medical care affects well-being.•Results show real-life patient insights on bladder problems in multiple sclerosis.•More awareness of the impact on bladder problems in multiple sclerosis is needed. Persons with multiple sclerosis (pwMS) frequently suffer from bladder problems that are not identified and managed optimally, reducing quality of life and increasing risk of health consequences. This study aimed to investigate associations between bladder problems and well-being of pwMS. The study included 1872 pwMS from France, Germany, Italy, and the UK self-reporting on demographics, MS status, bladder problems and management, and well-being. Logistic regression analyses were performed to investigate associations with self-reported well-being. Population mean age was 51 years and 79 % were women. Among pwMS, 55 % reported bladder problems indicating overactive bladder (OAB), and 40 % reported self-experienced urinary retention. Self-management of bladder problems was reported by 32 %, 33 % were yet to have problem resolution, and 45 % reported a wish to receive bladder management help. Additionally, 35 % of pwMS reported that bladder problem onset preceded awareness of a link to MS. OAB, problem self-management, and urinary complications were significantly associated with lower well-being. Bladder problems affect pwMS across disease subtypes and many attempt self-management. Consequently, pwMS with bladder problems are more likely to experience lower well-being, suggesting an unmet need. Raising awareness of the link between bladder problems and well-being could benefit pwMS living with bladder problems.