Experimental evidence that carbon-ion radiotherapy utilizes cytotoxic T lymphocyte-mediated anti-tumor immunity for shrinking tumors compared to X-ray therapy

The therapeutic efficacy of radiotherapy (RT) is primarily driven by two factors: biophysical DNA damage in cancer cells and radiation-induced anti-tumor immunity. However, Anti-tumor immune responses between X-ray RT (XRT) and carbon-ion RT (CIRT) remain unclear. In this study, we, employed mouse m...

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Veröffentlicht in:Biochemical and biophysical research communications 2024-07, Vol.718, p.150058, Article 150058
Hauptverfasser: Takeshima, Tsuguhide, Hirayama, Ryoichi, Hasegawa, Sumitaka
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Sprache:eng
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