Characterization of Biologic Discontinuation Among Pediatric Patients With Crohn’s Disease

Biologic therapies may effectively treat Crohn’s disease (CD), and pediatric patients who discontinue multiple biologics risk exhausting treatment options. The frequency and context of biologic discontinuation have not been well-characterized. We aimed to determine patterns of biologic use, disconti...

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Veröffentlicht in:	Clinical gastroenterology and hepatology 2024-10, Vol.22 (10), p.2075-2083.e1
Hauptverfasser:	Ali, Sabina, Pasternak, Brad, Moses, Jonathan, Suskind, David L., Samson, Charles, Kaplan, Jess, Creps, Jana, Manning, Lauren, Baker, Michaella, Singer, Dianne, Patel, Perseus, Trombler, Becca, Anandakrishnan, Archana, Khorrami, Camila, Feldman, Maya, McGoldrick, Molly, Adler, Jeremy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adalimumab - administration & dosage Adalimumab - therapeutic use Adolescent Biological Products - administration & dosage Biological Products - therapeutic use Child Crohn Disease - drug therapy Crohn’s Disease Drug Monitoring - methods Efficacy Female Humans Infliximab - administration & dosage Infliximab - therapeutic use Male Pediatric Prospective Studies Treatment Longevity United States Withholding Treatment - statistics & numerical data
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