The use of bispyridinium non-oxime analogues for the restoration of nerve agent impaired neuromuscular transmission in rat hemidiaphragms – Structure optimization

Organophosphate pesticide poisoning challenges health care systems worldwide. Furthermore, nerve agents remain a continuous threat. The treatment options for organophosphate poisoning have virtually been unchanged for decades, relying on symptomatic treatment and the use of oximes to indirectly rest...

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Veröffentlicht in:	Toxicology letters 2024-06, Vol.397, p.42-47
Hauptverfasser:	Amend, Niko, Timperley, Christopher M., Bird, Mike, Green, A.Christopher, Worek, Franz, Seeger, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase Bispyridinium non-oximes Nerve agent Nicotinic receptor Organophosphate
Online-Zugang:	Volltext
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