Growth and body composition of infants born moderate-to-late preterm fed a protein- and mineral-enriched postdischarge formula compared with a standard term formula until 6 months corrected age, a randomized controlled trial
Infants born moderate-to-late preterm (i.e., 32 wk–35 wk 6 d gestation) are, analogous to those born very preterm, at risk of later obesity, hypertension, and diabetes. Appropriate early life nutrition is key for ensuring optimal growth and body composition, thereby mitigating potential cardiometabo...
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| Veröffentlicht in: | The American journal of clinical nutrition 2024-07, Vol.120 (1), p.111-120 |
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| creator | van de Lagemaat, Monique Ruys, Charlotte A Muts, Jacqueline Finken, Martijn JJ Rotteveel, Joost van Goudoever, Johannes B Lafeber, Harrie N van den Akker, Chris HP Schrijver-Levie, Nathalie S Boonstra, Venje von Lindern, Jeanette S de Winter, Peter van Brakel, Monique J Drewes, Aernoud J Westra, Matthijs |
| description | Infants born moderate-to-late preterm (i.e., 32 wk–35 wk 6 d gestation) are, analogous to those born very preterm, at risk of later obesity, hypertension, and diabetes. Appropriate early life nutrition is key for ensuring optimal growth and body composition, thereby mitigating potential cardiometabolic risks.
We aimed to compare growth and body composition between infants born moderate-to-late preterm fed isocaloric but protein- and mineral-enriched postdischarge formula (PDF) or standard term formula (STF) until 6 mo corrected age (CA; i.e., after term equivalent age [TEA]).
After enrollment (≤7 d postpartum), infants received PDF if (fortified) mother’s own milk (MOM) was insufficient. At TEA, those receiving >25% of intake as formula were randomized to either continue the same PDF (n = 47) or switch to STF (n = 50); those receiving ≥75% of intake as MOM (n = 60) served as references. At TEA and 6 mo CA, we assessed anthropometry and body composition using both dual-energy x-ray absorptiometry (DXA) and air displacement plethysmography (ADP).
Feeding groups had similar gestational age (median [25th percentile;75th percentile]: 34.3 [33.5; 35.1] wk), birthweight (mean ± standard deviation [SD]: 2175 ± 412 g), anthropometry, and body composition at TEA. At 6 mo CA, infants fed PDF had slightly, but significantly, greater length (67.6 ± 2.5 and 66.9 ± 2.6 cm, P < 0.05) and larger head circumference (43.9 ± 1.3 and 43.4 ± 1.5 cm, P < 0.05) compared to infants fed STF. Also, infants fed PDF had higher lean mass (LM) and bone mineral content estimated by DXA (4772 ± 675 and 4502 ± 741 g; 140 ± 20 and 131 ± 23 g, respectively; P < 0.05). ADP estimates, however, were not statistically different between feeding groups.
Infants born moderate-to-late preterm demonstrated modest increases in length, head circumference, LM, and bone mineral content when fed PDF compared to STF for 6 mo after TEA.
This trial was registered at the International Clinical Trial Registry Platform as NTR5117 and NTR NL4979. |
| doi_str_mv | 10.1016/j.ajcnut.2024.04.035 |
| format | Article |
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We aimed to compare growth and body composition between infants born moderate-to-late preterm fed isocaloric but protein- and mineral-enriched postdischarge formula (PDF) or standard term formula (STF) until 6 mo corrected age (CA; i.e., after term equivalent age [TEA]).
After enrollment (≤7 d postpartum), infants received PDF if (fortified) mother’s own milk (MOM) was insufficient. At TEA, those receiving >25% of intake as formula were randomized to either continue the same PDF (n = 47) or switch to STF (n = 50); those receiving ≥75% of intake as MOM (n = 60) served as references. At TEA and 6 mo CA, we assessed anthropometry and body composition using both dual-energy x-ray absorptiometry (DXA) and air displacement plethysmography (ADP).
Feeding groups had similar gestational age (median [25th percentile;75th percentile]: 34.3 [33.5; 35.1] wk), birthweight (mean ± standard deviation [SD]: 2175 ± 412 g), anthropometry, and body composition at TEA. At 6 mo CA, infants fed PDF had slightly, but significantly, greater length (67.6 ± 2.5 and 66.9 ± 2.6 cm, P < 0.05) and larger head circumference (43.9 ± 1.3 and 43.4 ± 1.5 cm, P < 0.05) compared to infants fed STF. Also, infants fed PDF had higher lean mass (LM) and bone mineral content estimated by DXA (4772 ± 675 and 4502 ± 741 g; 140 ± 20 and 131 ± 23 g, respectively; P < 0.05). ADP estimates, however, were not statistically different between feeding groups.
Infants born moderate-to-late preterm demonstrated modest increases in length, head circumference, LM, and bone mineral content when fed PDF compared to STF for 6 mo after TEA.
This trial was registered at the International Clinical Trial Registry Platform as NTR5117 and NTR NL4979.</description><identifier>ISSN: 0002-9165</identifier><identifier>ISSN: 1938-3207</identifier><identifier>EISSN: 1938-3207</identifier><identifier>DOI: 10.1016/j.ajcnut.2024.04.035</identifier><identifier>PMID: 38719093</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Age ; air displacement plethysmography ; Anthropometry ; Birth weight ; Body Composition ; Bone mass ; Bone mineral content ; Child Development ; Circumferences ; Diabetes mellitus ; Dietary Proteins - administration & dosage ; Dual energy X-ray absorptiometry ; Female ; Gestational Age ; growth ; Health risks ; Humans ; Hypertension ; Infant ; Infant Formula - chemistry ; Infant Nutritional Physiological Phenomena ; Infant, Newborn ; Infant, Premature - growth & development ; Infants ; Male ; Minerals - administration & dosage ; moderate-to-late preterm ; mother’s own milk ; nutrition ; Plethysmography ; postdischarge ; protein ; Protein composition ; protein-enriched ; Proteins</subject><ispartof>The American journal of clinical nutrition, 2024-07, Vol.120 (1), p.111-120</ispartof><rights>2024 The Author(s)</rights><rights>Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.</rights><rights>Copyright American Society for Clinical Nutrition, Inc. Jul 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c315t-10575ffd193fb9615f95993ea2fe58b2b01a3b5fa1b950ae78046a55a0d867473</cites><orcidid>0000-0002-1588-6049</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38719093$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van de Lagemaat, Monique</creatorcontrib><creatorcontrib>Ruys, Charlotte A</creatorcontrib><creatorcontrib>Muts, Jacqueline</creatorcontrib><creatorcontrib>Finken, Martijn JJ</creatorcontrib><creatorcontrib>Rotteveel, Joost</creatorcontrib><creatorcontrib>van Goudoever, Johannes B</creatorcontrib><creatorcontrib>Lafeber, Harrie N</creatorcontrib><creatorcontrib>van den Akker, Chris HP</creatorcontrib><creatorcontrib>Schrijver-Levie, Nathalie S</creatorcontrib><creatorcontrib>Boonstra, Venje</creatorcontrib><creatorcontrib>von Lindern, Jeanette S</creatorcontrib><creatorcontrib>de Winter, Peter</creatorcontrib><creatorcontrib>van Brakel, Monique J</creatorcontrib><creatorcontrib>Drewes, Aernoud J</creatorcontrib><creatorcontrib>Westra, Matthijs</creatorcontrib><creatorcontrib>Late preterms and the Effects of postdischarge nutrition on Growth and Overall metabolic health (LEGO) study group</creatorcontrib><title>Growth and body composition of infants born moderate-to-late preterm fed a protein- and mineral-enriched postdischarge formula compared with a standard term formula until 6 months corrected age, a randomized controlled trial</title><title>The American journal of clinical nutrition</title><addtitle>Am J Clin Nutr</addtitle><description>Infants born moderate-to-late preterm (i.e., 32 wk–35 wk 6 d gestation) are, analogous to those born very preterm, at risk of later obesity, hypertension, and diabetes. Appropriate early life nutrition is key for ensuring optimal growth and body composition, thereby mitigating potential cardiometabolic risks.
We aimed to compare growth and body composition between infants born moderate-to-late preterm fed isocaloric but protein- and mineral-enriched postdischarge formula (PDF) or standard term formula (STF) until 6 mo corrected age (CA; i.e., after term equivalent age [TEA]).
After enrollment (≤7 d postpartum), infants received PDF if (fortified) mother’s own milk (MOM) was insufficient. At TEA, those receiving >25% of intake as formula were randomized to either continue the same PDF (n = 47) or switch to STF (n = 50); those receiving ≥75% of intake as MOM (n = 60) served as references. At TEA and 6 mo CA, we assessed anthropometry and body composition using both dual-energy x-ray absorptiometry (DXA) and air displacement plethysmography (ADP).
Feeding groups had similar gestational age (median [25th percentile;75th percentile]: 34.3 [33.5; 35.1] wk), birthweight (mean ± standard deviation [SD]: 2175 ± 412 g), anthropometry, and body composition at TEA. At 6 mo CA, infants fed PDF had slightly, but significantly, greater length (67.6 ± 2.5 and 66.9 ± 2.6 cm, P < 0.05) and larger head circumference (43.9 ± 1.3 and 43.4 ± 1.5 cm, P < 0.05) compared to infants fed STF. Also, infants fed PDF had higher lean mass (LM) and bone mineral content estimated by DXA (4772 ± 675 and 4502 ± 741 g; 140 ± 20 and 131 ± 23 g, respectively; P < 0.05). ADP estimates, however, were not statistically different between feeding groups.
Infants born moderate-to-late preterm demonstrated modest increases in length, head circumference, LM, and bone mineral content when fed PDF compared to STF for 6 mo after TEA.
This trial was registered at the International Clinical Trial Registry Platform as NTR5117 and NTR NL4979.</description><subject>Age</subject><subject>air displacement plethysmography</subject><subject>Anthropometry</subject><subject>Birth weight</subject><subject>Body Composition</subject><subject>Bone mass</subject><subject>Bone mineral content</subject><subject>Child Development</subject><subject>Circumferences</subject><subject>Diabetes mellitus</subject><subject>Dietary Proteins - administration & dosage</subject><subject>Dual energy X-ray absorptiometry</subject><subject>Female</subject><subject>Gestational Age</subject><subject>growth</subject><subject>Health risks</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Infant</subject><subject>Infant Formula - chemistry</subject><subject>Infant Nutritional Physiological Phenomena</subject><subject>Infant, Newborn</subject><subject>Infant, Premature - growth & development</subject><subject>Infants</subject><subject>Male</subject><subject>Minerals - administration & dosage</subject><subject>moderate-to-late preterm</subject><subject>mother’s own milk</subject><subject>nutrition</subject><subject>Plethysmography</subject><subject>postdischarge</subject><subject>protein</subject><subject>Protein composition</subject><subject>protein-enriched</subject><subject>Proteins</subject><issn>0002-9165</issn><issn>1938-3207</issn><issn>1938-3207</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ks9u1DAQxiMEokvhDRCyxIVDs4zjOH8uSKiiBakSFzhbTjzuepXYi-20Kk_LozDpLhw4IFly7Pl934wnUxSvOWw58Ob9fqv3o1_ytoKq3gItIZ8UG96LrhQVtE-LDQBUZc8beVa8SGkPwKu6a54XZ6JreQ-92BS_rmO4zzumvWFDMA9sDPMhJJdd8CxY5rzVPieKRc_mYDDqjGUO5UQ7O0TMGGdm0TBNp5DR-fLRbHae2KlEH924ozi5ZuPSuNPxFpkNcV4m_ZhORwrfu7UKljKJdTTs6HuiFp_dxBoqwOddIlGMOOY16S1ekCqSKMzuJ92MhMQwTfSZo9PTy-KZ1VPCV6f9vPh-9enb5efy5uv1l8uPN-UouMwlB9lKaw21zw59w6XtZd8L1JVF2Q3VAFyLQVrNh16CxraDutFSajBd09atOC_eHX2pCz8WTFnN9FicJu0xLEkJkIILyUVF6Nt_0H1YoqfqiOqqrgZoBFH1kRpjSCmiVYfoZh0fFAe1ToDaq-MEqHUCFNASkmRvTubLMKP5K_rzywn4cASQunHnMKo0OvQjGrc2VZng_p_hN09jyKI</recordid><startdate>202407</startdate><enddate>202407</enddate><creator>van de Lagemaat, Monique</creator><creator>Ruys, Charlotte A</creator><creator>Muts, Jacqueline</creator><creator>Finken, Martijn JJ</creator><creator>Rotteveel, Joost</creator><creator>van Goudoever, Johannes B</creator><creator>Lafeber, Harrie N</creator><creator>van den Akker, Chris HP</creator><creator>Schrijver-Levie, Nathalie S</creator><creator>Boonstra, Venje</creator><creator>von Lindern, Jeanette S</creator><creator>de Winter, Peter</creator><creator>van Brakel, Monique J</creator><creator>Drewes, Aernoud J</creator><creator>Westra, Matthijs</creator><general>Elsevier Inc</general><general>American Society for Clinical Nutrition, Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T7</scope><scope>7TS</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1588-6049</orcidid></search><sort><creationdate>202407</creationdate><title>Growth and body composition of infants born moderate-to-late preterm fed a protein- and mineral-enriched postdischarge formula compared with a standard term formula until 6 months corrected age, a randomized controlled trial</title><author>van de Lagemaat, Monique ; Ruys, Charlotte A ; Muts, Jacqueline ; Finken, Martijn JJ ; Rotteveel, Joost ; van Goudoever, Johannes B ; Lafeber, Harrie N ; van den Akker, Chris HP ; Schrijver-Levie, Nathalie S ; Boonstra, Venje ; von Lindern, Jeanette S ; de Winter, Peter ; van Brakel, Monique J ; Drewes, Aernoud J ; Westra, Matthijs</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c315t-10575ffd193fb9615f95993ea2fe58b2b01a3b5fa1b950ae78046a55a0d867473</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Age</topic><topic>air displacement plethysmography</topic><topic>Anthropometry</topic><topic>Birth weight</topic><topic>Body Composition</topic><topic>Bone mass</topic><topic>Bone mineral content</topic><topic>Child Development</topic><topic>Circumferences</topic><topic>Diabetes mellitus</topic><topic>Dietary Proteins - administration & dosage</topic><topic>Dual energy X-ray absorptiometry</topic><topic>Female</topic><topic>Gestational Age</topic><topic>growth</topic><topic>Health risks</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Infant</topic><topic>Infant Formula - chemistry</topic><topic>Infant Nutritional Physiological Phenomena</topic><topic>Infant, Newborn</topic><topic>Infant, Premature - growth & development</topic><topic>Infants</topic><topic>Male</topic><topic>Minerals - administration & dosage</topic><topic>moderate-to-late preterm</topic><topic>mother’s own milk</topic><topic>nutrition</topic><topic>Plethysmography</topic><topic>postdischarge</topic><topic>protein</topic><topic>Protein composition</topic><topic>protein-enriched</topic><topic>Proteins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van de Lagemaat, Monique</creatorcontrib><creatorcontrib>Ruys, Charlotte A</creatorcontrib><creatorcontrib>Muts, Jacqueline</creatorcontrib><creatorcontrib>Finken, Martijn JJ</creatorcontrib><creatorcontrib>Rotteveel, Joost</creatorcontrib><creatorcontrib>van Goudoever, Johannes B</creatorcontrib><creatorcontrib>Lafeber, Harrie N</creatorcontrib><creatorcontrib>van den Akker, Chris HP</creatorcontrib><creatorcontrib>Schrijver-Levie, Nathalie S</creatorcontrib><creatorcontrib>Boonstra, Venje</creatorcontrib><creatorcontrib>von Lindern, Jeanette S</creatorcontrib><creatorcontrib>de Winter, Peter</creatorcontrib><creatorcontrib>van Brakel, Monique J</creatorcontrib><creatorcontrib>Drewes, Aernoud J</creatorcontrib><creatorcontrib>Westra, Matthijs</creatorcontrib><creatorcontrib>Late preterms and the Effects of postdischarge nutrition on Growth and Overall metabolic health (LEGO) study group</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van de Lagemaat, Monique</au><au>Ruys, Charlotte A</au><au>Muts, Jacqueline</au><au>Finken, Martijn JJ</au><au>Rotteveel, Joost</au><au>van Goudoever, Johannes B</au><au>Lafeber, Harrie N</au><au>van den Akker, Chris HP</au><au>Schrijver-Levie, Nathalie S</au><au>Boonstra, Venje</au><au>von Lindern, Jeanette S</au><au>de Winter, Peter</au><au>van Brakel, Monique J</au><au>Drewes, Aernoud J</au><au>Westra, Matthijs</au><aucorp>Late preterms and the Effects of postdischarge nutrition on Growth and Overall metabolic health (LEGO) study group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Growth and body composition of infants born moderate-to-late preterm fed a protein- and mineral-enriched postdischarge formula compared with a standard term formula until 6 months corrected age, a randomized controlled trial</atitle><jtitle>The American journal of clinical nutrition</jtitle><addtitle>Am J Clin Nutr</addtitle><date>2024-07</date><risdate>2024</risdate><volume>120</volume><issue>1</issue><spage>111</spage><epage>120</epage><pages>111-120</pages><issn>0002-9165</issn><issn>1938-3207</issn><eissn>1938-3207</eissn><abstract>Infants born moderate-to-late preterm (i.e., 32 wk–35 wk 6 d gestation) are, analogous to those born very preterm, at risk of later obesity, hypertension, and diabetes. Appropriate early life nutrition is key for ensuring optimal growth and body composition, thereby mitigating potential cardiometabolic risks.
We aimed to compare growth and body composition between infants born moderate-to-late preterm fed isocaloric but protein- and mineral-enriched postdischarge formula (PDF) or standard term formula (STF) until 6 mo corrected age (CA; i.e., after term equivalent age [TEA]).
After enrollment (≤7 d postpartum), infants received PDF if (fortified) mother’s own milk (MOM) was insufficient. At TEA, those receiving >25% of intake as formula were randomized to either continue the same PDF (n = 47) or switch to STF (n = 50); those receiving ≥75% of intake as MOM (n = 60) served as references. At TEA and 6 mo CA, we assessed anthropometry and body composition using both dual-energy x-ray absorptiometry (DXA) and air displacement plethysmography (ADP).
Feeding groups had similar gestational age (median [25th percentile;75th percentile]: 34.3 [33.5; 35.1] wk), birthweight (mean ± standard deviation [SD]: 2175 ± 412 g), anthropometry, and body composition at TEA. At 6 mo CA, infants fed PDF had slightly, but significantly, greater length (67.6 ± 2.5 and 66.9 ± 2.6 cm, P < 0.05) and larger head circumference (43.9 ± 1.3 and 43.4 ± 1.5 cm, P < 0.05) compared to infants fed STF. Also, infants fed PDF had higher lean mass (LM) and bone mineral content estimated by DXA (4772 ± 675 and 4502 ± 741 g; 140 ± 20 and 131 ± 23 g, respectively; P < 0.05). ADP estimates, however, were not statistically different between feeding groups.
Infants born moderate-to-late preterm demonstrated modest increases in length, head circumference, LM, and bone mineral content when fed PDF compared to STF for 6 mo after TEA.
This trial was registered at the International Clinical Trial Registry Platform as NTR5117 and NTR NL4979.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>38719093</pmid><doi>10.1016/j.ajcnut.2024.04.035</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-1588-6049</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9165 |
| ispartof | The American journal of clinical nutrition, 2024-07, Vol.120 (1), p.111-120 |
| issn | 0002-9165 1938-3207 1938-3207 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3053135132 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Age air displacement plethysmography Anthropometry Birth weight Body Composition Bone mass Bone mineral content Child Development Circumferences Diabetes mellitus Dietary Proteins - administration & dosage Dual energy X-ray absorptiometry Female Gestational Age growth Health risks Humans Hypertension Infant Infant Formula - chemistry Infant Nutritional Physiological Phenomena Infant, Newborn Infant, Premature - growth & development Infants Male Minerals - administration & dosage moderate-to-late preterm mother’s own milk nutrition Plethysmography postdischarge protein Protein composition protein-enriched Proteins |
| title | Growth and body composition of infants born moderate-to-late preterm fed a protein- and mineral-enriched postdischarge formula compared with a standard term formula until 6 months corrected age, a randomized controlled trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T14%3A39%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Growth%20and%20body%20composition%20of%20infants%20born%20moderate-to-late%20preterm%20fed%20a%20protein-%20and%20mineral-enriched%20postdischarge%20formula%20compared%20with%20a%20standard%20term%20formula%20until%206%20months%20corrected%20age,%20a%20randomized%20controlled%20trial&rft.jtitle=The%20American%20journal%20of%20clinical%20nutrition&rft.au=van%20de%20Lagemaat,%20Monique&rft.aucorp=Late%20preterms%20and%20the%20Effects%20of%20postdischarge%20nutrition%20on%20Growth%20and%20Overall%20metabolic%20health%20(LEGO)%20study%20group&rft.date=2024-07&rft.volume=120&rft.issue=1&rft.spage=111&rft.epage=120&rft.pages=111-120&rft.issn=0002-9165&rft.eissn=1938-3207&rft_id=info:doi/10.1016/j.ajcnut.2024.04.035&rft_dat=%3Cproquest_cross%3E3082840063%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3082840063&rft_id=info:pmid/38719093&rft_els_id=S0002916524004611&rfr_iscdi=true |