The ICL1 and MLS1 Genes, Integral to the Glyoxylate Cycle, are Essential and Specific for Caloric Restriction‐Mediated Extension of Lifespan in Budding Yeast

The regulation of complex energy metabolism is intricately linked to cellular energy demands. Caloric restriction (CR) plays a pivotal role in modulating the expression of genes associated with key metabolic pathways, including glycolysis, the tricarboxylic acid (TCA) cycle, and the glyoxylate cycle...

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Veröffentlicht in:	Advanced biology 2024-09, Vol.8 (9), p.e2400083-n/a
Hauptverfasser:	Kwon, Young‐Yon, Lee, Han‐Jun, Lee, Myung‐Jin, Lee, Young‐Sam, Lee, Cheol‐Koo
Format:	Artikel
Sprache:	eng
Schlagworte:	Caloric Restriction Citric Acid Cycle - genetics Gene Expression Regulation, Fungal Glycolysis - genetics glyoxylate cycle Glyoxylates - metabolism Isocitrate Lyase - genetics Isocitrate Lyase - metabolism longevity Malate Synthase - genetics Malate Synthase - metabolism rapamycin Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism
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