Patterns of primary and secondary defects associated with non‐syndromic cleft lip and palate: An epidemiological analysis in a Kenyan population
Cleft lip and palate deformities substantially burden individuals and families, particularly in low‐income communities. However, a comprehensive understanding of the patterns and distribution of these deformities in Kenya remains limited. This retrospective cross‐sectional study analyzed 647 clinica...
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Veröffentlicht in: | Congenital anomalies 2024-05, Vol.64 (3), p.134-142 |
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description | Cleft lip and palate deformities substantially burden individuals and families, particularly in low‐income communities. However, a comprehensive understanding of the patterns and distribution of these deformities in Kenya remains limited. This retrospective cross‐sectional study analyzed 647 clinical records from the BelaRisu Foundation registry in Kenya, spanning 2018–2022. After meticulous record verification and data extraction, cleft pattern modeling was used to analyze each case. Data were imported to SPSS version 29.0 and descriptive statistics were calculated, which included means, ranges, frequencies, percentages, and standard deviations. Additionally, a comparative analysis between genders was conducted. The findings revealed a higher average age of presentation compared with previous studies in Kenya, along with a greater susceptibility of males to cleft lip and palate defects overall. Noteworthy disparities in case distribution across provinces were observed. Cleft lip emerged as the most observed primary defect, while palatal fistulae constituted the most frequent secondary defect. Interestingly, while some results aligned with global trends, others diverged significantly from the existing literature, warranting further exploration and investigation. These findings shed light on the unique patterns and distribution of cleft lip and palate deformities in Kenya, highlighting the need for targeted interventions and support systems. |
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However, a comprehensive understanding of the patterns and distribution of these deformities in Kenya remains limited. This retrospective cross‐sectional study analyzed 647 clinical records from the BelaRisu Foundation registry in Kenya, spanning 2018–2022. After meticulous record verification and data extraction, cleft pattern modeling was used to analyze each case. Data were imported to SPSS version 29.0 and descriptive statistics were calculated, which included means, ranges, frequencies, percentages, and standard deviations. Additionally, a comparative analysis between genders was conducted. The findings revealed a higher average age of presentation compared with previous studies in Kenya, along with a greater susceptibility of males to cleft lip and palate defects overall. Noteworthy disparities in case distribution across provinces were observed. Cleft lip emerged as the most observed primary defect, while palatal fistulae constituted the most frequent secondary defect. Interestingly, while some results aligned with global trends, others diverged significantly from the existing literature, warranting further exploration and investigation. 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However, a comprehensive understanding of the patterns and distribution of these deformities in Kenya remains limited. This retrospective cross‐sectional study analyzed 647 clinical records from the BelaRisu Foundation registry in Kenya, spanning 2018–2022. After meticulous record verification and data extraction, cleft pattern modeling was used to analyze each case. Data were imported to SPSS version 29.0 and descriptive statistics were calculated, which included means, ranges, frequencies, percentages, and standard deviations. Additionally, a comparative analysis between genders was conducted. The findings revealed a higher average age of presentation compared with previous studies in Kenya, along with a greater susceptibility of males to cleft lip and palate defects overall. Noteworthy disparities in case distribution across provinces were observed. Cleft lip emerged as the most observed primary defect, while palatal fistulae constituted the most frequent secondary defect. Interestingly, while some results aligned with global trends, others diverged significantly from the existing literature, warranting further exploration and investigation. These findings shed light on the unique patterns and distribution of cleft lip and palate deformities in Kenya, highlighting the need for targeted interventions and support systems.</description><subject>cleft lip</subject><subject>Cleft lip/palate</subject><subject>cleft palate</subject><subject>Comparative analysis</subject><subject>Defects</subject><subject>Epidemiology</subject><subject>Fistulae</subject><subject>patterns</subject><subject>secondary defects</subject><subject>Statistical analysis</subject><subject>Support systems</subject><issn>0914-3505</issn><issn>1741-4520</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp10c1qFTEYBuAgij1WF96ABNzUxbT5PzPuDget0oIudD3k55uakknGyQxldl6CeIm9EnN-2oVgNiF8T15IXoReU3JOy7qwN_qcMqnEE7Sia0ErIRl5ilakoaLiksgT9CLnW0KYUmvyHJ3wWnJChVqhP1_1NMEYM04dHkbf63HBOjqcwabodicHHdgpY51zsl5P4PCdn37gmOL9r995iW5MvbfYBugmHPywvz_oUOh7vIkYBu-g9ymkG291KGMdluwz9hFrfAVx0REPaZjLDZ_iS_Ss0yHDq-N-ir5__PBt-6m6_nL5ebu5riwTXFTGOOkabWhDZE2sEIY1tjHEUmVlU7NGMcWhNsooobkyWhroysQSw4DXmp-is0PuMKafM-Sp7X22EIKOkObcciKpYIqsRaFv_6G3aR7LM_aqCMXpTr07KDumnEfo2uOHtpS0u6LaUlS7L6rYN8fE2fTgHuVDMwVcHMCdD7D8P6ndXm4OkX8By4qfZg</recordid><startdate>202405</startdate><enddate>202405</enddate><creator>Kamau, Martin</creator><creator>Sarna, Krishan</creator><creator>Guthua, Symon</creator><creator>Sonigra, Khushboo Jayant</creator><creator>Kimani, Paul</creator><general>John Wiley & Sons Australia, Ltd</general><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4369-093X</orcidid></search><sort><creationdate>202405</creationdate><title>Patterns of primary and secondary defects associated with non‐syndromic cleft lip and palate: An epidemiological analysis in a Kenyan population</title><author>Kamau, Martin ; Sarna, Krishan ; Guthua, Symon ; Sonigra, Khushboo Jayant ; Kimani, Paul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2434-bbd5d9ab190580c44b29c9b0c16c598296263e8b6b64a36ba5befc59c0b2e38a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>cleft lip</topic><topic>Cleft lip/palate</topic><topic>cleft palate</topic><topic>Comparative analysis</topic><topic>Defects</topic><topic>Epidemiology</topic><topic>Fistulae</topic><topic>patterns</topic><topic>secondary defects</topic><topic>Statistical analysis</topic><topic>Support systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kamau, Martin</creatorcontrib><creatorcontrib>Sarna, Krishan</creatorcontrib><creatorcontrib>Guthua, Symon</creatorcontrib><creatorcontrib>Sonigra, Khushboo Jayant</creatorcontrib><creatorcontrib>Kimani, Paul</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Congenital anomalies</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kamau, Martin</au><au>Sarna, Krishan</au><au>Guthua, Symon</au><au>Sonigra, Khushboo Jayant</au><au>Kimani, Paul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Patterns of primary and secondary defects associated with non‐syndromic cleft lip and palate: An epidemiological analysis in a Kenyan population</atitle><jtitle>Congenital anomalies</jtitle><addtitle>Congenit Anom (Kyoto)</addtitle><date>2024-05</date><risdate>2024</risdate><volume>64</volume><issue>3</issue><spage>134</spage><epage>142</epage><pages>134-142</pages><issn>0914-3505</issn><eissn>1741-4520</eissn><abstract>Cleft lip and palate deformities substantially burden individuals and families, particularly in low‐income communities. However, a comprehensive understanding of the patterns and distribution of these deformities in Kenya remains limited. This retrospective cross‐sectional study analyzed 647 clinical records from the BelaRisu Foundation registry in Kenya, spanning 2018–2022. After meticulous record verification and data extraction, cleft pattern modeling was used to analyze each case. Data were imported to SPSS version 29.0 and descriptive statistics were calculated, which included means, ranges, frequencies, percentages, and standard deviations. Additionally, a comparative analysis between genders was conducted. The findings revealed a higher average age of presentation compared with previous studies in Kenya, along with a greater susceptibility of males to cleft lip and palate defects overall. Noteworthy disparities in case distribution across provinces were observed. Cleft lip emerged as the most observed primary defect, while palatal fistulae constituted the most frequent secondary defect. Interestingly, while some results aligned with global trends, others diverged significantly from the existing literature, warranting further exploration and investigation. These findings shed light on the unique patterns and distribution of cleft lip and palate deformities in Kenya, highlighting the need for targeted interventions and support systems.</abstract><cop>Kyoto, Japan</cop><pub>John Wiley & Sons Australia, Ltd</pub><pmid>38530146</pmid><doi>10.1111/cga.12564</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-4369-093X</orcidid></addata></record> |
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subjects | cleft lip Cleft lip/palate cleft palate Comparative analysis Defects Epidemiology Fistulae patterns secondary defects Statistical analysis Support systems |
title | Patterns of primary and secondary defects associated with non‐syndromic cleft lip and palate: An epidemiological analysis in a Kenyan population |
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