Vaginal and Rectal microbiome changes following administration of a multi-species antenatal probiotic: A randomized control trial

The gut and vaginal microbiome undergo changes during pregnancy which may be protective or harmful to the birthing person. Probiotics have been found to cause protective changes to the gut and vaginal microbiomes, with the potential to improve perinatal outcomes. This randomized control trial compar...

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Veröffentlicht in:Gut microbes reports 2024, Vol.1 (1), p.1-10
Hauptverfasser: Malloy, Emily, Kates, Ashley E, Dixon, Jonah, Riley, Colleen, Safdar, Nasia, Hanson, Lisa
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container_title Gut microbes reports
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creator Malloy, Emily
Kates, Ashley E
Dixon, Jonah
Riley, Colleen
Safdar, Nasia
Hanson, Lisa
description The gut and vaginal microbiome undergo changes during pregnancy which may be protective or harmful to the birthing person. Probiotics have been found to cause protective changes to the gut and vaginal microbiomes, with the potential to improve perinatal outcomes. This randomized control trial compares the vaginal and rectal microbiomes before and after an antenatal probiotic or placebo intervention, with a diverse group of pregnant people and a special focus on racial disparities. The vaginal and rectal microbiomes reveal non-significant increased in the probiotics group, with a greater increase in participants who identified as Black. Potential implications and future study are discussed.
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subjects group B Streptococcus
Pregnancy
probiotics
racial disparities
vaginal microbiome
title Vaginal and Rectal microbiome changes following administration of a multi-species antenatal probiotic: A randomized control trial
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