Clinical relevance of subthreshold PTSD versus full criteria PTSD following traumatic brain injury in U.S. service members and veterans

The purpose of this cross-sectional study was to examine the influence of subthreshold posttraumatic stress disorder (PTSD) and full PTSD on quality of life following mild traumatic brain injury (mTBI). Participants were 734 service members and veterans (SMV) classified into two injury groups: uncom...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of affective disorders 2024-08, Vol.358, p.408-415
Hauptverfasser: French, Louis M., Brickell, Tracey A., Lippa, Sara M., Rogers, Alicia A., Cristaudo, Kendal E., Walker, Thomas T., Higgins, Molly, Bailie, Jason M., Kennedy, Jan, Hungerford, Lars, Lange, Rael T.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 415
container_issue
container_start_page 408
container_title Journal of affective disorders
container_volume 358
creator French, Louis M.
Brickell, Tracey A.
Lippa, Sara M.
Rogers, Alicia A.
Cristaudo, Kendal E.
Walker, Thomas T.
Higgins, Molly
Bailie, Jason M.
Kennedy, Jan
Hungerford, Lars
Lange, Rael T.
description The purpose of this cross-sectional study was to examine the influence of subthreshold posttraumatic stress disorder (PTSD) and full PTSD on quality of life following mild traumatic brain injury (mTBI). Participants were 734 service members and veterans (SMV) classified into two injury groups: uncomplicated mild TBI (MTBI; n = 596) and injured controls (IC, n = 139). Participants completed a battery of neurobehavioral measures, 12-or-more months post-injury, that included the PTSD Checklist Civilian version, Neurobehavioral Symptom Inventory, and select scales from the TBI-QOL and MPAI. The MTBI group was divided into three PTSD subgroups: No-PTSD (n = 266), Subthreshold PTSD (n = 139), and Full-PTSD (n = 190). There was a linear relationship between PTSD severity and neurobehavioral functioning/quality of life in the MTBI sample. As PTSD severity increased, significantly worse scores were found on 11 of the 12 measures (i.e., MTBI: Full-PTSD > Sub-PTSD > No-PTSD). When considering the number of clinically elevated scores, a linear relationship between PTSD severity and neurobehavioral functioning/quality of life was again observed in the MTBI sample (e.g., 3-or-more elevated scores: Full-PTSD = 92.1 %, Sub-PTSD = 61.9 %, No-PTSD = 19.9 %). Limitations included the use of a self-report measure to determine diagnostic status that may under/overcount or mischaracterize individuals. PTSD symptoms, whether at the level of diagnosable PTSD, or falling short of that because of the intensity or characterization of symptoms, have a significant negative impact on one's quality of life following MTBI. Clinicians' treatment targets should focus on the symptoms that are most troubling for an individual and the individual's perception of quality of life, regardless of the diagnosis itself.
doi_str_mv 10.1016/j.jad.2024.05.015
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3051423635</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0165032724007341</els_id><sourcerecordid>3051423635</sourcerecordid><originalsourceid>FETCH-LOGICAL-c338t-fb22c56268cf087b2023f9a195ee73e0c3c15d81b0806f6ba467e283084da93c3</originalsourceid><addsrcrecordid>eNp9kE1LxDAQQIMoun78AC-So5fWSbJpu3iS9RMEBfUc0nSiKWmrSbviL_BvG1n16GkO8-bBPEIOGeQMWHHS5q1ucg58noPMgckNMmOyFBmXrNwks8TIDAQvd8hujC0AFIsStsmOqEqQkssZ-Vx61zujPQ3ocaV7g3SwNE71-BIwvgy-ofePD-d0hSFOkdrJe2qCGzE4vd7Ywfvh3fXPdAx66vToDK2Ddj11fTuFjzToU_6Q04hh5ZK_w65ONqr7JmmTSfdxn2xZ7SMe_Mw98nR58bi8zm7vrm6WZ7eZEaIaM1tzbmTBi8pYqMo6_S7sQrOFRCwFghGGyaZiNVRQ2KLW86JEXgmo5o1eCCP2yPHa-xqGtwnjqDoXDXqvexymqARINueiEDKhbI2aMMQY0KrX4DodPhQD9d1ftSr1V9_9FUiV-qebox_9VHfY_F38Bk_A6RrA9OTKYVDROEzVGxfQjKoZ3D_6L8_QlsQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3051423635</pqid></control><display><type>article</type><title>Clinical relevance of subthreshold PTSD versus full criteria PTSD following traumatic brain injury in U.S. service members and veterans</title><source>Elsevier ScienceDirect Journals Complete</source><creator>French, Louis M. ; Brickell, Tracey A. ; Lippa, Sara M. ; Rogers, Alicia A. ; Cristaudo, Kendal E. ; Walker, Thomas T. ; Higgins, Molly ; Bailie, Jason M. ; Kennedy, Jan ; Hungerford, Lars ; Lange, Rael T.</creator><creatorcontrib>French, Louis M. ; Brickell, Tracey A. ; Lippa, Sara M. ; Rogers, Alicia A. ; Cristaudo, Kendal E. ; Walker, Thomas T. ; Higgins, Molly ; Bailie, Jason M. ; Kennedy, Jan ; Hungerford, Lars ; Lange, Rael T.</creatorcontrib><description>The purpose of this cross-sectional study was to examine the influence of subthreshold posttraumatic stress disorder (PTSD) and full PTSD on quality of life following mild traumatic brain injury (mTBI). Participants were 734 service members and veterans (SMV) classified into two injury groups: uncomplicated mild TBI (MTBI; n = 596) and injured controls (IC, n = 139). Participants completed a battery of neurobehavioral measures, 12-or-more months post-injury, that included the PTSD Checklist Civilian version, Neurobehavioral Symptom Inventory, and select scales from the TBI-QOL and MPAI. The MTBI group was divided into three PTSD subgroups: No-PTSD (n = 266), Subthreshold PTSD (n = 139), and Full-PTSD (n = 190). There was a linear relationship between PTSD severity and neurobehavioral functioning/quality of life in the MTBI sample. As PTSD severity increased, significantly worse scores were found on 11 of the 12 measures (i.e., MTBI: Full-PTSD &gt; Sub-PTSD &gt; No-PTSD). When considering the number of clinically elevated scores, a linear relationship between PTSD severity and neurobehavioral functioning/quality of life was again observed in the MTBI sample (e.g., 3-or-more elevated scores: Full-PTSD = 92.1 %, Sub-PTSD = 61.9 %, No-PTSD = 19.9 %). Limitations included the use of a self-report measure to determine diagnostic status that may under/overcount or mischaracterize individuals. PTSD symptoms, whether at the level of diagnosable PTSD, or falling short of that because of the intensity or characterization of symptoms, have a significant negative impact on one's quality of life following MTBI. Clinicians' treatment targets should focus on the symptoms that are most troubling for an individual and the individual's perception of quality of life, regardless of the diagnosis itself.</description><identifier>ISSN: 0165-0327</identifier><identifier>ISSN: 1573-2517</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/j.jad.2024.05.015</identifier><identifier>PMID: 38705525</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Mild traumatic brain injury ; Neurobehavioral ; Posttraumatic stress ; Subthreshold PTSD</subject><ispartof>Journal of affective disorders, 2024-08, Vol.358, p.408-415</ispartof><rights>2024</rights><rights>Copyright © 2024. Published by Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c338t-fb22c56268cf087b2023f9a195ee73e0c3c15d81b0806f6ba467e283084da93c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jad.2024.05.015$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38705525$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>French, Louis M.</creatorcontrib><creatorcontrib>Brickell, Tracey A.</creatorcontrib><creatorcontrib>Lippa, Sara M.</creatorcontrib><creatorcontrib>Rogers, Alicia A.</creatorcontrib><creatorcontrib>Cristaudo, Kendal E.</creatorcontrib><creatorcontrib>Walker, Thomas T.</creatorcontrib><creatorcontrib>Higgins, Molly</creatorcontrib><creatorcontrib>Bailie, Jason M.</creatorcontrib><creatorcontrib>Kennedy, Jan</creatorcontrib><creatorcontrib>Hungerford, Lars</creatorcontrib><creatorcontrib>Lange, Rael T.</creatorcontrib><title>Clinical relevance of subthreshold PTSD versus full criteria PTSD following traumatic brain injury in U.S. service members and veterans</title><title>Journal of affective disorders</title><addtitle>J Affect Disord</addtitle><description>The purpose of this cross-sectional study was to examine the influence of subthreshold posttraumatic stress disorder (PTSD) and full PTSD on quality of life following mild traumatic brain injury (mTBI). Participants were 734 service members and veterans (SMV) classified into two injury groups: uncomplicated mild TBI (MTBI; n = 596) and injured controls (IC, n = 139). Participants completed a battery of neurobehavioral measures, 12-or-more months post-injury, that included the PTSD Checklist Civilian version, Neurobehavioral Symptom Inventory, and select scales from the TBI-QOL and MPAI. The MTBI group was divided into three PTSD subgroups: No-PTSD (n = 266), Subthreshold PTSD (n = 139), and Full-PTSD (n = 190). There was a linear relationship between PTSD severity and neurobehavioral functioning/quality of life in the MTBI sample. As PTSD severity increased, significantly worse scores were found on 11 of the 12 measures (i.e., MTBI: Full-PTSD &gt; Sub-PTSD &gt; No-PTSD). When considering the number of clinically elevated scores, a linear relationship between PTSD severity and neurobehavioral functioning/quality of life was again observed in the MTBI sample (e.g., 3-or-more elevated scores: Full-PTSD = 92.1 %, Sub-PTSD = 61.9 %, No-PTSD = 19.9 %). Limitations included the use of a self-report measure to determine diagnostic status that may under/overcount or mischaracterize individuals. PTSD symptoms, whether at the level of diagnosable PTSD, or falling short of that because of the intensity or characterization of symptoms, have a significant negative impact on one's quality of life following MTBI. Clinicians' treatment targets should focus on the symptoms that are most troubling for an individual and the individual's perception of quality of life, regardless of the diagnosis itself.</description><subject>Mild traumatic brain injury</subject><subject>Neurobehavioral</subject><subject>Posttraumatic stress</subject><subject>Subthreshold PTSD</subject><issn>0165-0327</issn><issn>1573-2517</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LxDAQQIMoun78AC-So5fWSbJpu3iS9RMEBfUc0nSiKWmrSbviL_BvG1n16GkO8-bBPEIOGeQMWHHS5q1ucg58noPMgckNMmOyFBmXrNwks8TIDAQvd8hujC0AFIsStsmOqEqQkssZ-Vx61zujPQ3ocaV7g3SwNE71-BIwvgy-ofePD-d0hSFOkdrJe2qCGzE4vd7Ywfvh3fXPdAx66vToDK2Ddj11fTuFjzToU_6Q04hh5ZK_w65ONqr7JmmTSfdxn2xZ7SMe_Mw98nR58bi8zm7vrm6WZ7eZEaIaM1tzbmTBi8pYqMo6_S7sQrOFRCwFghGGyaZiNVRQ2KLW86JEXgmo5o1eCCP2yPHa-xqGtwnjqDoXDXqvexymqARINueiEDKhbI2aMMQY0KrX4DodPhQD9d1ftSr1V9_9FUiV-qebox_9VHfY_F38Bk_A6RrA9OTKYVDROEzVGxfQjKoZ3D_6L8_QlsQ</recordid><startdate>20240801</startdate><enddate>20240801</enddate><creator>French, Louis M.</creator><creator>Brickell, Tracey A.</creator><creator>Lippa, Sara M.</creator><creator>Rogers, Alicia A.</creator><creator>Cristaudo, Kendal E.</creator><creator>Walker, Thomas T.</creator><creator>Higgins, Molly</creator><creator>Bailie, Jason M.</creator><creator>Kennedy, Jan</creator><creator>Hungerford, Lars</creator><creator>Lange, Rael T.</creator><general>Elsevier B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20240801</creationdate><title>Clinical relevance of subthreshold PTSD versus full criteria PTSD following traumatic brain injury in U.S. service members and veterans</title><author>French, Louis M. ; Brickell, Tracey A. ; Lippa, Sara M. ; Rogers, Alicia A. ; Cristaudo, Kendal E. ; Walker, Thomas T. ; Higgins, Molly ; Bailie, Jason M. ; Kennedy, Jan ; Hungerford, Lars ; Lange, Rael T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-fb22c56268cf087b2023f9a195ee73e0c3c15d81b0806f6ba467e283084da93c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Mild traumatic brain injury</topic><topic>Neurobehavioral</topic><topic>Posttraumatic stress</topic><topic>Subthreshold PTSD</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>French, Louis M.</creatorcontrib><creatorcontrib>Brickell, Tracey A.</creatorcontrib><creatorcontrib>Lippa, Sara M.</creatorcontrib><creatorcontrib>Rogers, Alicia A.</creatorcontrib><creatorcontrib>Cristaudo, Kendal E.</creatorcontrib><creatorcontrib>Walker, Thomas T.</creatorcontrib><creatorcontrib>Higgins, Molly</creatorcontrib><creatorcontrib>Bailie, Jason M.</creatorcontrib><creatorcontrib>Kennedy, Jan</creatorcontrib><creatorcontrib>Hungerford, Lars</creatorcontrib><creatorcontrib>Lange, Rael T.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>French, Louis M.</au><au>Brickell, Tracey A.</au><au>Lippa, Sara M.</au><au>Rogers, Alicia A.</au><au>Cristaudo, Kendal E.</au><au>Walker, Thomas T.</au><au>Higgins, Molly</au><au>Bailie, Jason M.</au><au>Kennedy, Jan</au><au>Hungerford, Lars</au><au>Lange, Rael T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical relevance of subthreshold PTSD versus full criteria PTSD following traumatic brain injury in U.S. service members and veterans</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>2024-08-01</date><risdate>2024</risdate><volume>358</volume><spage>408</spage><epage>415</epage><pages>408-415</pages><issn>0165-0327</issn><issn>1573-2517</issn><eissn>1573-2517</eissn><abstract>The purpose of this cross-sectional study was to examine the influence of subthreshold posttraumatic stress disorder (PTSD) and full PTSD on quality of life following mild traumatic brain injury (mTBI). Participants were 734 service members and veterans (SMV) classified into two injury groups: uncomplicated mild TBI (MTBI; n = 596) and injured controls (IC, n = 139). Participants completed a battery of neurobehavioral measures, 12-or-more months post-injury, that included the PTSD Checklist Civilian version, Neurobehavioral Symptom Inventory, and select scales from the TBI-QOL and MPAI. The MTBI group was divided into three PTSD subgroups: No-PTSD (n = 266), Subthreshold PTSD (n = 139), and Full-PTSD (n = 190). There was a linear relationship between PTSD severity and neurobehavioral functioning/quality of life in the MTBI sample. As PTSD severity increased, significantly worse scores were found on 11 of the 12 measures (i.e., MTBI: Full-PTSD &gt; Sub-PTSD &gt; No-PTSD). When considering the number of clinically elevated scores, a linear relationship between PTSD severity and neurobehavioral functioning/quality of life was again observed in the MTBI sample (e.g., 3-or-more elevated scores: Full-PTSD = 92.1 %, Sub-PTSD = 61.9 %, No-PTSD = 19.9 %). Limitations included the use of a self-report measure to determine diagnostic status that may under/overcount or mischaracterize individuals. PTSD symptoms, whether at the level of diagnosable PTSD, or falling short of that because of the intensity or characterization of symptoms, have a significant negative impact on one's quality of life following MTBI. Clinicians' treatment targets should focus on the symptoms that are most troubling for an individual and the individual's perception of quality of life, regardless of the diagnosis itself.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>38705525</pmid><doi>10.1016/j.jad.2024.05.015</doi><tpages>8</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0165-0327
ispartof Journal of affective disorders, 2024-08, Vol.358, p.408-415
issn 0165-0327
1573-2517
1573-2517
language eng
recordid cdi_proquest_miscellaneous_3051423635
source Elsevier ScienceDirect Journals Complete
subjects Mild traumatic brain injury
Neurobehavioral
Posttraumatic stress
Subthreshold PTSD
title Clinical relevance of subthreshold PTSD versus full criteria PTSD following traumatic brain injury in U.S. service members and veterans
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T07%3A19%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20relevance%20of%20subthreshold%20PTSD%20versus%20full%20criteria%20PTSD%20following%20traumatic%20brain%20injury%20in%20U.S.%20service%20members%20and%20veterans&rft.jtitle=Journal%20of%20affective%20disorders&rft.au=French,%20Louis%20M.&rft.date=2024-08-01&rft.volume=358&rft.spage=408&rft.epage=415&rft.pages=408-415&rft.issn=0165-0327&rft.eissn=1573-2517&rft_id=info:doi/10.1016/j.jad.2024.05.015&rft_dat=%3Cproquest_cross%3E3051423635%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3051423635&rft_id=info:pmid/38705525&rft_els_id=S0165032724007341&rfr_iscdi=true