Current Status and Perspectives of Therapeutic Antibodies Targeting the Spike Protein S2 Subunit against SARS-CoV-2

The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has devastated public health and the global economy. New variants are continually emerging because of amino acid mutations within the SARS-CoV-2 spike protein. Existing ne...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2024/05/01, Vol.47(5), pp.917-923
Hauptverfasser:	Yamamoto, Yuichiro, Inoue, Tetsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Antibodies Antibodies, Neutralizing - immunology Antibodies, Neutralizing - therapeutic use Antibodies, Viral - immunology Antibodies, Viral - therapeutic use bispecific antibody Coronaviruses COVID-19 COVID-19 - immunology Cross-protection fusion peptide Global economy Humans Mutation neutralizing antibody Proteins Public health S2 subunit SARS-CoV-2 - immunology Severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike Glycoprotein, Coronavirus - genetics Spike Glycoprotein, Coronavirus - immunology Spike protein stem helix
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