Resveratrol alleviates inorganic arsenic-induced ferroptosis in chicken brain via activation of the Nrf2 signaling pathway

Inorganic arsenic (iAs) is a well-recognized environmental pollutant that induces severe brain injury in humans and animals. The antioxidant, anti-inflammatory, and anti-ferroptotic effects of resveratrol (Res) were demonstrated in multiple animal experiments. In order to investigate the protective...

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Veröffentlicht in:	Pesticide biochemistry and physiology 2024-05, Vol.201, p.105885-105885, Article 105885
Hauptverfasser:	Pang, Shan, Han, Biqi, Wu, Pengfei, Yang, Xu, Liu, Yunfeng, Li, Jiayi, Lv, Zhanjun, Zhang, Zhigang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Arsenic Arsenic - toxicity Brain Brain - drug effects Brain - metabolism Brain - pathology Chickens Female Ferroptosis Ferroptosis - drug effects NF-E2-Related Factor 2 - metabolism NF-kappa B - metabolism Nrf2 Oxidative Stress - drug effects Resveratrol Resveratrol - pharmacology Signal Transduction - drug effects
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