Effects of quercetin in preclinical models of Parkinson's disease: A systematic review

Parkinson's disease (PD) is a neurodegenerative disease that affects dopaminergic neurons, thus impairing dopaminergic signalling. Quercetin (QUE) has antioxidant and neuroprotective properties that are promising for the treatment of PD. This systematic review aimed to investigate the therapeut...

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Veröffentlicht in:	Basic & clinical pharmacology & toxicology 2024-07, Vol.135 (1), p.3-22
Hauptverfasser:	Oliveira Vian, Camila, Marinho, Marcelo Augusto Germani, Silva Marques, Magno, Hort, Mariana Appel, Cordeiro, Marcos Freitas, Horn, Ana Paula
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Antioxidants - pharmacology Antioxidants - therapeutic use Apoptosis Apoptosis - drug effects Disease Models, Animal Dopamine receptors flavonoids Humans Inflammation Mice Movement disorders Neurodegenerative diseases Neuroprotection Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Oxidative stress Oxidative Stress - drug effects Oxidopamine Parkinson Disease - drug therapy Parkinson's disease Parkinsonian Disorders - chemically induced Parkinsonian Disorders - drug therapy Parkinsonian Disorders - physiopathology Quercetin Quercetin - pharmacology Rats Rotenone Signal transduction Systematic review
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