What Have We Learned about the Prevention of NMSC from Albino Patients from Malawi? Secondary Prevention Maintained over Time
We have conducted cooperative campaigns focusing on albino patients in a rural area of Malawi. What have we learned? Three surgical campaigns were performed in Nkhotakota district (2019-2023). Albino clinical and tumor characteristics were collected. Between 22 and 75 albinos were evaluated in each...
Gespeichert in:
| Veröffentlicht in: | Cancers 2024-04, Vol.16 (8), p.1522 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 8 |
| container_start_page | 1522 |
| container_title | Cancers |
| container_volume | 16 |
| creator | Tomás-Velázquez, Alejandra Moreno-Artero, Ester Romero, Javier Escalonilla, Pilar Medina, Isabel Petiti, Gisela Hebe Redondo, Pedro |
| description | We have conducted cooperative campaigns focusing on albino patients in a rural area of Malawi. What have we learned?
Three surgical campaigns were performed in Nkhotakota district (2019-2023). Albino clinical and tumor characteristics were collected.
Between 22 and 75 albinos were evaluated in each campaign (mean age < 28 years old). Most patients did not use sunscreen in a way that provided optimal photoprotection. Regarding tumors, the proportion of basal and squamous cell carcinomas ranged from 1:1 to almost 2:1. Of 156 albino patients, 34 attended more than once. However, of the 19 patients with 30 tumors operated on in 2021, only seven were assessed the following year (12 were lost to follow-up). At least 14 albinos with locally advanced tumors were evaluated.
Distributing photoprotective clothing could be more efficient or perhaps an earlier measure of sunscreen in rural Africa as it does not require permanent repositioning. Very-high-risk patients (previous interventions with positive margins or high-risk tumors, intense actinic damage, and new tumors constantly appearing, especially those presenting SCCs) require close follow-up and treatment and represent our main target. Secondary prevention with Malawian collaboration and the use of teledermatology is essential for patient tracking, as they are able to offer curative treatments. |
| doi_str_mv | 10.3390/cancers16081522 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3047951003</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3047951003</sourcerecordid><originalsourceid>FETCH-LOGICAL-c320t-52aac3d3189e6e817c7bf2ea5e32d4f2b99216d5e5732804d61c0e189ebbbf4f3</originalsourceid><addsrcrecordid>eNpdkd9LwzAQx4Mobsw9-yYBX3yZy482aZ9kDHXCpoNN9ljS9Mo62mQm7cQH_3c7NkV2EO7Ife5Lcl-Erim55zwmQ62MBuepIBENGTtDXUYkGwgRB-f_6g7qe78hbXBOpZCXqMMjIZkgQRd9r9aqxhO1A7wCPAXlDGRYpbapcb0GPHewA1MX1mCb49fZYoxzZys8KtPCWDxXddG2_eFypkr1WTzgBWhrMuW-_o_PVGHq9rTydgcOL4sKrtBFrkoP_WPuofenx-V4Mpi-Pb-MR9OB5ozUg5AppXnGaRSDgIhKLdOcgQqBsyzIWRrHjIoshFByFpEgE1QT2NNpmuZBznvo7qC7dfajAV8nVeE1lKUyYBufcBLIOKT7DfXQ7Qm6sY0z7ev2lJA0DrhsqeGB0s567yBPtq6o2h8nlCR7c5ITc9qJm6Nuk1aQ_fG_VvAfe06LXA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3046719437</pqid></control><display><type>article</type><title>What Have We Learned about the Prevention of NMSC from Albino Patients from Malawi? Secondary Prevention Maintained over Time</title><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>PubMed Central</source><source>EZB Electronic Journals Library</source><source>PubMed Central Open Access</source><creator>Tomás-Velázquez, Alejandra ; Moreno-Artero, Ester ; Romero, Javier ; Escalonilla, Pilar ; Medina, Isabel ; Petiti, Gisela Hebe ; Redondo, Pedro</creator><creatorcontrib>Tomás-Velázquez, Alejandra ; Moreno-Artero, Ester ; Romero, Javier ; Escalonilla, Pilar ; Medina, Isabel ; Petiti, Gisela Hebe ; Redondo, Pedro</creatorcontrib><description>We have conducted cooperative campaigns focusing on albino patients in a rural area of Malawi. What have we learned?
Three surgical campaigns were performed in Nkhotakota district (2019-2023). Albino clinical and tumor characteristics were collected.
Between 22 and 75 albinos were evaluated in each campaign (mean age < 28 years old). Most patients did not use sunscreen in a way that provided optimal photoprotection. Regarding tumors, the proportion of basal and squamous cell carcinomas ranged from 1:1 to almost 2:1. Of 156 albino patients, 34 attended more than once. However, of the 19 patients with 30 tumors operated on in 2021, only seven were assessed the following year (12 were lost to follow-up). At least 14 albinos with locally advanced tumors were evaluated.
Distributing photoprotective clothing could be more efficient or perhaps an earlier measure of sunscreen in rural Africa as it does not require permanent repositioning. Very-high-risk patients (previous interventions with positive margins or high-risk tumors, intense actinic damage, and new tumors constantly appearing, especially those presenting SCCs) require close follow-up and treatment and represent our main target. Secondary prevention with Malawian collaboration and the use of teledermatology is essential for patient tracking, as they are able to offer curative treatments.</description><identifier>ISSN: 2072-6694</identifier><identifier>EISSN: 2072-6694</identifier><identifier>DOI: 10.3390/cancers16081522</identifier><identifier>PMID: 38672604</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Albinism ; Cooperation ; Dermatology ; Immunocompetence ; Melanoma ; Oncology ; Patients ; Prevention ; Radiation ; Risk groups ; Rural areas ; Skin cancer ; Squamous cell carcinoma ; Sunscreen ; Surgery ; Tumors</subject><ispartof>Cancers, 2024-04, Vol.16 (8), p.1522</ispartof><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c320t-52aac3d3189e6e817c7bf2ea5e32d4f2b99216d5e5732804d61c0e189ebbbf4f3</cites><orcidid>0000-0002-9216-4461 ; 0000-0001-7899-2511</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38672604$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tomás-Velázquez, Alejandra</creatorcontrib><creatorcontrib>Moreno-Artero, Ester</creatorcontrib><creatorcontrib>Romero, Javier</creatorcontrib><creatorcontrib>Escalonilla, Pilar</creatorcontrib><creatorcontrib>Medina, Isabel</creatorcontrib><creatorcontrib>Petiti, Gisela Hebe</creatorcontrib><creatorcontrib>Redondo, Pedro</creatorcontrib><title>What Have We Learned about the Prevention of NMSC from Albino Patients from Malawi? Secondary Prevention Maintained over Time</title><title>Cancers</title><addtitle>Cancers (Basel)</addtitle><description>We have conducted cooperative campaigns focusing on albino patients in a rural area of Malawi. What have we learned?
Three surgical campaigns were performed in Nkhotakota district (2019-2023). Albino clinical and tumor characteristics were collected.
Between 22 and 75 albinos were evaluated in each campaign (mean age < 28 years old). Most patients did not use sunscreen in a way that provided optimal photoprotection. Regarding tumors, the proportion of basal and squamous cell carcinomas ranged from 1:1 to almost 2:1. Of 156 albino patients, 34 attended more than once. However, of the 19 patients with 30 tumors operated on in 2021, only seven were assessed the following year (12 were lost to follow-up). At least 14 albinos with locally advanced tumors were evaluated.
Distributing photoprotective clothing could be more efficient or perhaps an earlier measure of sunscreen in rural Africa as it does not require permanent repositioning. Very-high-risk patients (previous interventions with positive margins or high-risk tumors, intense actinic damage, and new tumors constantly appearing, especially those presenting SCCs) require close follow-up and treatment and represent our main target. Secondary prevention with Malawian collaboration and the use of teledermatology is essential for patient tracking, as they are able to offer curative treatments.</description><subject>Albinism</subject><subject>Cooperation</subject><subject>Dermatology</subject><subject>Immunocompetence</subject><subject>Melanoma</subject><subject>Oncology</subject><subject>Patients</subject><subject>Prevention</subject><subject>Radiation</subject><subject>Risk groups</subject><subject>Rural areas</subject><subject>Skin cancer</subject><subject>Squamous cell carcinoma</subject><subject>Sunscreen</subject><subject>Surgery</subject><subject>Tumors</subject><issn>2072-6694</issn><issn>2072-6694</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkd9LwzAQx4Mobsw9-yYBX3yZy482aZ9kDHXCpoNN9ljS9Mo62mQm7cQH_3c7NkV2EO7Ife5Lcl-Erim55zwmQ62MBuepIBENGTtDXUYkGwgRB-f_6g7qe78hbXBOpZCXqMMjIZkgQRd9r9aqxhO1A7wCPAXlDGRYpbapcb0GPHewA1MX1mCb49fZYoxzZys8KtPCWDxXddG2_eFypkr1WTzgBWhrMuW-_o_PVGHq9rTydgcOL4sKrtBFrkoP_WPuofenx-V4Mpi-Pb-MR9OB5ozUg5AppXnGaRSDgIhKLdOcgQqBsyzIWRrHjIoshFByFpEgE1QT2NNpmuZBznvo7qC7dfajAV8nVeE1lKUyYBufcBLIOKT7DfXQ7Qm6sY0z7ev2lJA0DrhsqeGB0s567yBPtq6o2h8nlCR7c5ITc9qJm6Nuk1aQ_fG_VvAfe06LXA</recordid><startdate>20240416</startdate><enddate>20240416</enddate><creator>Tomás-Velázquez, Alejandra</creator><creator>Moreno-Artero, Ester</creator><creator>Romero, Javier</creator><creator>Escalonilla, Pilar</creator><creator>Medina, Isabel</creator><creator>Petiti, Gisela Hebe</creator><creator>Redondo, Pedro</creator><general>MDPI AG</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7TO</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9216-4461</orcidid><orcidid>https://orcid.org/0000-0001-7899-2511</orcidid></search><sort><creationdate>20240416</creationdate><title>What Have We Learned about the Prevention of NMSC from Albino Patients from Malawi? Secondary Prevention Maintained over Time</title><author>Tomás-Velázquez, Alejandra ; Moreno-Artero, Ester ; Romero, Javier ; Escalonilla, Pilar ; Medina, Isabel ; Petiti, Gisela Hebe ; Redondo, Pedro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c320t-52aac3d3189e6e817c7bf2ea5e32d4f2b99216d5e5732804d61c0e189ebbbf4f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Albinism</topic><topic>Cooperation</topic><topic>Dermatology</topic><topic>Immunocompetence</topic><topic>Melanoma</topic><topic>Oncology</topic><topic>Patients</topic><topic>Prevention</topic><topic>Radiation</topic><topic>Risk groups</topic><topic>Rural areas</topic><topic>Skin cancer</topic><topic>Squamous cell carcinoma</topic><topic>Sunscreen</topic><topic>Surgery</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tomás-Velázquez, Alejandra</creatorcontrib><creatorcontrib>Moreno-Artero, Ester</creatorcontrib><creatorcontrib>Romero, Javier</creatorcontrib><creatorcontrib>Escalonilla, Pilar</creatorcontrib><creatorcontrib>Medina, Isabel</creatorcontrib><creatorcontrib>Petiti, Gisela Hebe</creatorcontrib><creatorcontrib>Redondo, Pedro</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>ProQuest research library</collection><collection>ProQuest Biological Science Journals</collection><collection>Research Library (Corporate)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Cancers</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tomás-Velázquez, Alejandra</au><au>Moreno-Artero, Ester</au><au>Romero, Javier</au><au>Escalonilla, Pilar</au><au>Medina, Isabel</au><au>Petiti, Gisela Hebe</au><au>Redondo, Pedro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>What Have We Learned about the Prevention of NMSC from Albino Patients from Malawi? Secondary Prevention Maintained over Time</atitle><jtitle>Cancers</jtitle><addtitle>Cancers (Basel)</addtitle><date>2024-04-16</date><risdate>2024</risdate><volume>16</volume><issue>8</issue><spage>1522</spage><pages>1522-</pages><issn>2072-6694</issn><eissn>2072-6694</eissn><abstract>We have conducted cooperative campaigns focusing on albino patients in a rural area of Malawi. What have we learned?
Three surgical campaigns were performed in Nkhotakota district (2019-2023). Albino clinical and tumor characteristics were collected.
Between 22 and 75 albinos were evaluated in each campaign (mean age < 28 years old). Most patients did not use sunscreen in a way that provided optimal photoprotection. Regarding tumors, the proportion of basal and squamous cell carcinomas ranged from 1:1 to almost 2:1. Of 156 albino patients, 34 attended more than once. However, of the 19 patients with 30 tumors operated on in 2021, only seven were assessed the following year (12 were lost to follow-up). At least 14 albinos with locally advanced tumors were evaluated.
Distributing photoprotective clothing could be more efficient or perhaps an earlier measure of sunscreen in rural Africa as it does not require permanent repositioning. Very-high-risk patients (previous interventions with positive margins or high-risk tumors, intense actinic damage, and new tumors constantly appearing, especially those presenting SCCs) require close follow-up and treatment and represent our main target. Secondary prevention with Malawian collaboration and the use of teledermatology is essential for patient tracking, as they are able to offer curative treatments.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>38672604</pmid><doi>10.3390/cancers16081522</doi><orcidid>https://orcid.org/0000-0002-9216-4461</orcidid><orcidid>https://orcid.org/0000-0001-7899-2511</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2072-6694 |
| ispartof | Cancers, 2024-04, Vol.16 (8), p.1522 |
| issn | 2072-6694 2072-6694 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3047951003 |
| source | MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central; EZB Electronic Journals Library; PubMed Central Open Access |
| subjects | Albinism Cooperation Dermatology Immunocompetence Melanoma Oncology Patients Prevention Radiation Risk groups Rural areas Skin cancer Squamous cell carcinoma Sunscreen Surgery Tumors |
| title | What Have We Learned about the Prevention of NMSC from Albino Patients from Malawi? Secondary Prevention Maintained over Time |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T10%3A49%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=What%20Have%20We%20Learned%20about%20the%20Prevention%20of%20NMSC%20from%20Albino%20Patients%20from%20Malawi?%20Secondary%20Prevention%20Maintained%20over%20Time&rft.jtitle=Cancers&rft.au=Tom%C3%A1s-Vel%C3%A1zquez,%20Alejandra&rft.date=2024-04-16&rft.volume=16&rft.issue=8&rft.spage=1522&rft.pages=1522-&rft.issn=2072-6694&rft.eissn=2072-6694&rft_id=info:doi/10.3390/cancers16081522&rft_dat=%3Cproquest_cross%3E3047951003%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3046719437&rft_id=info:pmid/38672604&rfr_iscdi=true |