Protection against Oxidative Stress by Coenzyme Q10 in a Porcine Retinal Degeneration Model

Oxidative stress plays an important role in neurodegenerative diseases, including glaucoma. Therefore, we analyzed if the antioxidant coenzyme Q10 (CoQ10), which is also commercially available, can prevent retinal degeneration induced by hydrogen peroxide (H O ) in a porcine organ culture model. Ret...

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Veröffentlicht in:	Journal of personalized medicine 2024-04, Vol.14 (4), p.437
Hauptverfasser:	Deppe, Leonie, Mueller-Buehl, Ana M, Tsai, Teresa, Erb, Carl, Dick, H Burkhard, Joachim, Stephanie C
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cell culture Coenzyme Q10 Diabetic retinopathy Enzymes Explants Glaucoma Hydrogen peroxide Inflammation Macular degeneration Medical research Microglia mRNA Neurodegeneration Neurodegenerative diseases Neuroprotection Organ culture Oxidative stress Pathology Physiological aspects Retina Retinal degeneration Retinal ganglion cells Scientific equipment and supplies industry Signal transduction
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