DNA G-Quadruplex in NRP1 Promoter Facilitates SARS-CoV-2 Infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection continues to raise concerns worldwide. Numerous host factors involved in SARS-CoV-2 infection have been identified, but the regulatory mechanisms of these host factor remain unclear. Here, we report the role of G-quadruplexes (G4...

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Veröffentlicht in:	International journal of molecular sciences 2024-04, Vol.25 (8), p.4422
Hauptverfasser:	Gong, Pihai, Zhang, Rongxin, Xiao, Ke, Shu, Huiling, Li, Xinxiu, Fan, Hong, Sun, Xiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Coronaviruses COVID-19 COVID-19 - genetics COVID-19 - virology DNA E2F1 Transcription Factor - genetics E2F1 Transcription Factor - metabolism Epithelial Cells - metabolism Epithelial Cells - virology Experiments G-Quadruplexes Health aspects Humans Infections Medical research Medicine, Experimental Neuropilin-1 - genetics Neuropilin-1 - metabolism Pandemics Promoter Regions, Genetic Proteins RNA RNA sequencing SARS-CoV-2 - physiology Scientific equipment and supplies industry Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Virus Internalization Viruses
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