Hyaluronan-based hydrogel delivering glucose to mesenchymal stem cells intended to treat osteoarthritis

[Display omitted] Mesenchymal stem cell (MSC) therapy shows promise in regenerative medicine. For osteoarthritis (OA), MSCs delivered to the joint have a temporal window in which they can secrete growth factors and extracellular matrix molecules, contributing to cartilage regeneration and cell proli...

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Veröffentlicht in:	International journal of pharmaceutics 2024-05, Vol.657, p.124139-124139, Article 124139
Hauptverfasser:	Gonzalez-Fernandez, Paula, Simula, Luca, Jenni, Sébastien, Jordan, Olivier, Allémann, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta-Glucosidase - metabolism Cell Survival - drug effects Cells, Cultured Glucose Glucose - metabolism Humans Hyaluronic acid Hyaluronic Acid - chemistry Hydrogels - chemistry Mesenchymal stem cell Mesenchymal Stem Cell Transplantation - methods Mesenchymal Stem Cells Osteoarthritis Osteoarthritis - therapy Regenerative cell therapy
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