Fundamental evaluation regarding the relationship between albumin-binding and tumor accumulation of PSMA-targeting radioligands

Objective The marked success of prostate-specific membrane antigen (PSMA)-targeting radioligands with albumin binder (ALB) is attributed to the improvement of blood retention and tumor accumulation. [ 111 In]In-PNT-DA1, our PSMA-targeting radioligand with ALB, also achieved improved tumor accumulati...

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Veröffentlicht in:Annals of nuclear medicine 2024-07, Vol.38 (7), p.574-583
Hauptverfasser: Kazuta, Nobuki, Tsuchihashi, Shohei, Watanabe, Hiroyuki, Ono, Masahiro
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Sprache:eng
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