Deep sequencing identified miR-193b-3p as a positive regulator of autophagy targeting Akt3 in Ctenopharyngodon idella CIK cells during GCRV infection

Recent research has highlighted complex and close interaction between miRNAs, autophagy, and viral infection. In this study, we observed the autophagy status in CIK cells infected with GCRV at various time points. We found that GCRV consistently induced cellar autophagy from 0 h to 12 h post infecti...

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Veröffentlicht in:	Fish & shellfish immunology 2024-06, Vol.149, p.109586-109586, Article 109586
Hauptverfasser:	Yu, Hongyan, Chen, Zheyan, Liu, Yuting, Shen, Yubang, Gui, Lang, Qiu, Junqiang, Xu, Xiaoyan, Li, Jiale
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Carps - genetics Carps - immunology Cell Line Ctenopharyngodon idella enzymes fish Fish Diseases - immunology Fish Diseases - virology Fish Proteins - genetics Fish Proteins - immunology fluorescence GCRV gene expression Gene Expression Regulation - immunology genes Grass carp High-Throughput Nucleotide Sequencing immunity microRNA MicroRNAs - genetics MicroRNAs - immunology miRNAs prediction Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - immunology Proto-Oncogene Proteins c-akt - metabolism Reoviridae - physiology Reoviridae Infections - immunology Reoviridae Infections - veterinary shellfish viruses
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