Lymphangioleiomyomatosis as a potent lung cancer risk factor: Insights from a Japanese large cohort study

Background and Objective Lymphangioleiomyomatosis (LAM) is a rare neoplastic disease associated with the functional tumour suppressor genes TSC1 and TSC2 and causes structural destruction in the lungs, which could potentially increase the risk of lung cancer. However, this relationship remains uncle...

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Veröffentlicht in:	Respirology (Carlton, Vic.) Vic.), 2024-09, Vol.29 (9), p.815-824
Hauptverfasser:	Torasawa, Masahiro, Shukuya, Takehito, Uemura, Kohei, Hayashi, Takuo, Ueno, Toshihide, Kohsaka, Shinji, Masui, Yoshihiro, Shirai, Yukina, Okura, Makiko, Asao, Tetsuhiko, Mitsuishi, Yoichiro, Shimada, Naoko, Takahashi, Fumiyuki, Takamochi, Kazuya, Suzuki, Kenji, Takahashi, Kazuhisa, Seyama, Kuniaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Carcinogenesis Cohort Studies Diagnosis East Asian People ErbB-2 protein Female Humans Incidence Japan - epidemiology Lung cancer Lung diseases Lung Neoplasms - epidemiology Lung Neoplasms - genetics lymphangioleiomyomatosis Lymphangioleiomyomatosis - epidemiology Lymphangioleiomyomatosis - genetics Male Middle Aged rare lung diseases Registries Risk Factors Structure-function relationships TSC1 TSC2 Tuberous sclerosis Tumor suppressor genes Tumors tumour suppressor gene
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