Synergistic action of vitamin D3 and A on motor activity regulation in mice model of extrapyramidal syndrome: Correlational insights into astrocyte regulation, cytokine modulation, and dopaminergic activity

Extrapyramidal syndromes (EPS) represent neurological side effects of antipsychotic medications, characterized by motor disturbances. While previous studies have indicated the neuroprotective effects of vitamin D and A against EPS, the underlying mechanisms of this protection remain unclear. Twenty-...

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Veröffentlicht in:	Journal of chemical neuroanatomy 2024-07, Vol.138, p.102421, Article 102421
Hauptverfasser:	Sirajo, Mujittapha U., Maigari, Yahya K., Sunusi, Abdulrashid, Jibril, Adam N., Lawal, Isa Usman, Ibrahim, Badamasi M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activated astrocytes Animals Astrocytes - drug effects Astrocytes - metabolism Basal Ganglia Diseases - chemically induced Basal Ganglia Diseases - metabolism Cholecalciferol - pharmacology Corticobasal loop Cytokines - metabolism Disease Models, Animal Dopamine - metabolism Extrapyramidal syndrome Inflammation Male Mice Motor Activity - drug effects
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