DeepSeq2Drug: An expandable ensemble end-to-end anti-viral drug repurposing benchmark framework by multi-modal embeddings and transfer learning

Drug repurposing is promising in multiple scenarios, such as emerging viral outbreak controls and cost reductions of drug discovery. Traditional graph-based drug repurposing methods are limited to fast, large-scale virtual screens, as they constrain the counts for drugs and targets and fail to predi...

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Veröffentlicht in:Computers in biology and medicine 2024-06, Vol.175, p.108487, Article 108487
Hauptverfasser: Xie, Weidun, Yu, Jixiang, Huang, Lei, For, Lek Shyuen, Zheng, Zetian, Chen, Xingjian, Wang, Yuchen, Liu, Zhichao, Peng, Chengbin, Wong, Ka-Chun
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