Ultra-Low-Dose UV-C Photo-stimulation Promotes Neural Stem Cells Differentiation via Presenilin 1 Mediated Notch and β-Catenin Activation

Light-based photo-stimulation has demonstrated promising effects on stem cell behavior, particularly in optimizing neurogenesis. However, the precise parameters for achieving optimal results, including the wavelengths, light intensity, radiating energy, and underlying mechanisms, remain incompletely...

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Veröffentlicht in:	Molecular neurobiology 2024-11, Vol.61 (11), p.9491-9506
Hauptverfasser:	Zhou, Lin, Wang, Zihan, Zhong, Qiuling, Song, Bing, Wang, Yan, Guan, Teng, Liu, Qian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta Catenin - metabolism Biomedical and Life Sciences Biomedicine Cell activation Cell Biology Cell differentiation Cell Differentiation - radiation effects Cell proliferation Cell Proliferation - radiation effects Dose-Response Relationship, Radiation Light intensity Mice Neural stem cells Neural Stem Cells - metabolism Neural Stem Cells - radiation effects Neurobiology Neurogenesis Neurogenesis - radiation effects Neurology Neuromodulation Neurosciences Presenilin 1 Presenilin-1 - metabolism Receptor, Notch1 - metabolism Receptors, Notch - metabolism Stem cells Ultraviolet Rays β-Catenin
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