Acetate Assistance in Regioselective Hydroamination of Allenamides: A Combined Experimental and Density Functional Theory Study

A key factor in the development of selective nucleophilic addition to allenamides is controlling the reactivity of electrophilic intermediates, which is generally achieved using an electrophilic activator via conjugated iminium intermediates. In this combined experimental and computational study, we...

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Veröffentlicht in:Journal of organic chemistry 2024-05, Vol.89 (9), p.5927-5940
Hauptverfasser: Pradhan, Tapas R., Farah, Abdikani Omar, Sagar, Kadiyala, Wise, Henry R., Srimannarayana, Malempati, Cheong, Paul Ha-Yeon, Park, Jin Kyoon
Format: Artikel
Sprache:eng
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