Polycatechols inhibit ferroptosis and modulate tau liquid-liquid phase separation to mitigate Alzheimer's disease

Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects learning, memory, and cognition. Current treatments targeting amyloid-β (Aβ) and tau have shown limited effectiveness, necessitating further research on the aggregation and toxicity mechanisms. One of these mechanisms...

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Veröffentlicht in:Materials horizons 2024-07, Vol.11 (13), p.382-389
Hauptverfasser: Moorthy, Hariharan, Ramesh, Madhu, Padhi, Dikshaa, Baruah, Prayasee, Govindaraju, Thimmaiah
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Sprache:eng
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