Using the genomic adjusted radiation dose (GARD) to personalize the radiation dose in nasopharyngeal cancer

•GARD is associated with locoregional control in NPC and may serve as a potential framework to personalize radiotherapy dose.•Radiosensitive tumors for which GARD-optimized doses were estimated at less than the current standard (74 Gy) (14.1 %). Locally advanced nasopharyngeal cancer (NPC) patients...

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Veröffentlicht in:Radiotherapy and oncology 2024-07, Vol.196, p.110287, Article 110287
Hauptverfasser: Chiang, Chi Leung, Chan, Kenneth Sik Kwan, Li, Huaping, Ng, Wai Tong, Chow, James Chung Hang, Choi, Horace Cheuk Wai, Lam, Ka On, Lee, Victor Ho Fun, Ngan, Roger Kai Cheong, Lee, Anne Wing Mui, Eschrich, Steven A, Torres-Roca, Javier F, Wong, Jason Wing Hon
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Sprache:eng
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