Angiotensin II and dengue
Dengue is a disease caused by a flavivirus that is transmitted principally by the bite of an Aedes aegypti mosquito and represents a major public-health problem. Many studies have been carried out to identify soluble factors that are involved in the pathogenesis of this infection. Cytokines, soluble...
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| Veröffentlicht in: | Archives of virology 2023-07, Vol.168 (7), p.191-191, Article 191 |
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| creator | Mosquera-Sulbaran, Jesus A Pedreañez, Adriana Hernandez-Fonseca, Juan Pablo Hernandez-Fonseca, Hugo |
| description | Dengue is a disease caused by a flavivirus that is transmitted principally by the bite of an
Aedes aegypti
mosquito and represents a major public-health problem. Many studies have been carried out to identify soluble factors that are involved in the pathogenesis of this infection. Cytokines, soluble factors, and oxidative stress have been reported to be involved in the development of severe disease. Angiotensin II (Ang II) is a hormone with the ability to induce the production of cytokines and soluble factors related to the inflammatory processes and coagulation disorders observed in dengue. However, a direct involvement of Ang II in this disease has not been demonstrated. This review primarily summarizes the pathophysiology of dengue, the role of Ang II in various diseases, and reports that are highly suggestive of the involvement of this hormone in dengue. |
| doi_str_mv | 10.1007/s00705-023-05814-6 |
| format | Article |
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Aedes aegypti
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| subjects | Aedes aegypti Angiotensin Angiotensin II Apoptosis Biomedical and Life Sciences Biomedicine coagulation Cytokine storm Cytokines dengue Dengue fever Disease disease severity Enzymes Flavivirus Growth factors Immune system Infections Infectious Diseases Liver Lymphatic system Medical Microbiology Mosquitoes Oxidative stress Pathogenesis pathophysiology Permeability Public health Review Severe acute respiratory syndrome coronavirus 2 Thrombocytopenia Viral infections Virology |
| title | Angiotensin II and dengue |
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