Methylmercury directly modifies the 105th cysteine residue in oncostatin M to promote binding to tumor necrosis factor receptor 3 and inhibit cell growth

We previously found that methylmercury induces expression of oncostatin M (OSM), which is released extracellularly and binds to tumor necrosis factor receptor 3 (TNFR3), possibly enhancing its own toxicity. However, the mechanism by which methylmercury causes OSM to bind to TNFR3 rather than to its...

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Veröffentlicht in:Archives of toxicology 2023-07, Vol.97 (7), p.1887-1897
Hauptverfasser: Toyama, Takashi, Xu, Sidi, Kanemitsu, Yoshitomi, Hasegawa, Takashi, Noguchi, Takuya, Lee, Jin-Yong, Matsuzawa, Atsushi, Naganuma, Akira, Hwang, Gi-Wook
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Sprache:eng
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