LoC-SERS Platform Integrated with the Signal Amplification Strategy toward Parkinson’s Disease Diagnosis

Multiplexed detection of Parkinson’s disease (PD) biomarkers is of great significance for early diagnosis and personalized treatment. In this study, we fabricated a robust surface-enhanced Raman scattering-enabled lab-on-a-chip (LoC-SERS) platform for simultaneous quantification of α-synuclein, phos...

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Veröffentlicht in:	ACS applied materials & interfaces 2023-05, Vol.15 (18), p.21830-21842
Hauptverfasser:	Cao, Xiaowei, Ge, Shengjie, Chen, Miao, Mao, Haiyan, Wang, Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and Medical Applications of Materials and Interfaces biomarkers Biomarkers - analysis detection limit DNA early diagnosis Gold - chemistry lab-on-a-chip technology Limit of Detection Metal Nanoparticles - chemistry Mice osteocalcin osteopontin Parkinson Disease - diagnosis Reproducibility of Results silicon Silicon - chemistry Spectrum Analysis, Raman - methods tau Proteins
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