Chlorpyrifos induces placental oxidative stress and barrier dysfunction by mediating mitochondrial apoptosis via the ERK/MAPK signaling pathway: In vitro and in vivo studies

Chlorpyrifos (CPF) is an organophosphorus pesticide that is widely used in agricultural production and residential environments worldwide. In this study, we determined the harmful effects and toxicological mechanism of CPF in porcine trophectoderm (pTr) cells and the placenta of female mice during p...

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Veröffentlicht in:	The Science of the total environment 2023-08
Hauptverfasser:	Bai, Jun, Deng, Siwei, Fu, Huiyang, Yang, Qing, Ren, Fazheng, Zeng, Shenming, Chen, Zhaohui, Yang, Ying, Wu, Zhenlong
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis cell viability chlorpyrifos environment females flow cytometry lactate dehydrogenase membrane potential mitochondria mitochondrial membrane oxidative stress phenotype placenta pregnancy reactive oxygen species reproductive toxicology risk swine
Online-Zugang:	Volltext
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