Exploring management and outcomes of elderly patients with glioblastoma using data from two randomised trials (GEINO1401/EX-TEM)

Purpose The impact of age on optimal management of glioblastoma remains unclear. A recent combined analysis of two randomised trials, GEINO14-01 and EX-TEM, found no benefit from extending post-radiation temozolomide in newly diagnosed glioblastoma. Here, we explore the impact of age. Methods Releva...

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Veröffentlicht in:	Journal of neuro-oncology 2024-06, Vol.168 (2), p.299-306
Hauptverfasser:	Gately, Lucy, Mesía, C., Sepúlveda, J. M., del Barco, S., Pineda, E., Gironés, R., Fuster, J., Dumas, M., Gill, S., Navarro, L. M., Herrero, A., Dowling, A., de las Peñas, R., Vaz, M. A., Alonso, M., Lwin, Z., Harrup, R., Peralta, S., Long, A., Perez-Segura, P., Ahern, E., Garate, C. O., Wong, M., Campbell, R., Cuff, K., Jennens, R., Gallego, O., Underhill, C., Martinez-Garcia, M., Covela, M., Cooper, A., Brown, S., Rosenthal, M., Torres, J., Collins, I. M., Gibbs, P., Balana, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Bevacizumab Chemoradiotherapy Clinical trials Glioblastoma Glioma Medicine Medicine & Public Health Neurology Oncology Patients Post-radiation Statistical analysis Survival Temozolomide
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