MIF/NR3C2 axis regulates glucose metabolism reprogramming in pancreatic cancer through MAPK–ERK and AP-1 pathways

Abstract Inflammation and aberrant cellular metabolism are widely recognized as hallmarks of cancer. In pancreatic ductal adenocarcinoma (PDAC), inflammatory signaling and metabolic reprogramming are tightly interwoven, playing pivotal roles in the pathogenesis and progression of the disease. Howeve...

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Veröffentlicht in:Carcinogenesis (New York) 2024-08, Vol.45 (8), p.582-594
Hauptverfasser: Yang, Shouhui, Tang, Wei, Azizian, Azadeh, Gaedcke, Jochen, Ohara, Yuuki, Cawley, Helen, Hanna, Nader, Ghadimi, Michael, Lal, Trisha, Sen, Subrata, Creighton, Chad J, Gao, Jianjun, Putluri, Nagireddy, Ambs, Stefan, Hussain, Perwez
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Sprache:eng
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