Germline potential should not be overlooked for cancer variants identified in tumour-only somatic mutation testing

DNA sequencing of tumour tissue has become the standard care for many solid cancers because of the option to detect somatic variants that have significant therapeutic, diagnostic and prognostic implications. Variants found within the tumour may be either somatic or germline in origin. Somatic cancer...

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Veröffentlicht in:	Pathology 2024-06, Vol.56 (4), p.468-472
Hauptverfasser:	Al-Shinnag, Mohammad, Cheong, Pak Leng, Goodwin, Annabel, Trent, Ronald, Yu, Bing
Format:	Artikel
Sprache:	eng
Schlagworte:	germline pathogenic variants Somatic mutation testing somatic variants tumour-only sequencing
Online-Zugang:	Volltext
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