CAR-T cell expansion platforms yield distinct T cell differentiation states

With investigators looking to expand engineered T cell therapies such as CAR-T to new tumor targets and patient populations, a variety of cell manufacturing platforms have been developed to scale manufacturing capacity using closed and/or automated systems. Such platforms are particularly useful for...

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Veröffentlicht in:	Cytotherapy (Oxford, England) England), 2024-07, Vol.26 (7), p.757-768
Hauptverfasser:	Song, Hannah W., Prochazkova, Michaela, Shao, Lipei, Traynor, Roshini, Underwood, Sarah, Black, Mary, Fellowes, Vicki, Shi, Rongye, Pouzolles, Marie, Chou, Hsien-Chao, Cheuk, Adam T., Taylor, Naomi, Jin, Ping, Somerville, Robert P., Stroncek, David F., Khan, Javed, Highfill, Steven L.
Format:	Artikel
Sprache:	eng
Schlagworte:	CAR-T cells cell expansion cell manufacturing chimeric antigen receptor hypoxia
Online-Zugang:	Volltext
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