Mijiao formula regulates NAT10-mediated Runx2 mRNA ac4C modification to promote bone marrow mesenchymal stem cell osteogenic differentiation and improve osteoporosis in ovariectomized rats

The Mijiao (MJ) formula, a traditional herbal remedy, incorporates antlers as its primary constituent. It can effectively treat osteoporosis (OP), anti-aging, enhance immune activity, and change depression-like behavior. In this study, we investigated that MJ formula is a comprehensive treatment str...

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Veröffentlicht in:	Journal of ethnopharmacology 2024-08, Vol.330, p.118191-118191, Article 118191
Hauptverfasser:	Xiao, Dong, Huang, Sirui, Tang, Zhuqian, Liu, Mengqiu, Di, Di, Ma, Yingrun, Li, Yunjuan, Duan, Jin-Ao, Lu, Cai, Zhao, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - drug effects Cells, Cultured Core Binding Factor Alpha 1 Subunit - genetics Core Binding Factor Alpha 1 Subunit - metabolism Disease Models, Animal Drugs, Chinese Herbal - pharmacology Female Mesenchymal Stem Cells - drug effects Mijiao formula NAT10 Osteogenesis - drug effects Osteoporosis Osteoporosis - drug therapy Ovariectomy Rats Rats, Sprague-Dawley RNA, Messenger - metabolism Runx2
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