Insights into membrane interactions and their therapeutic potential
Recent research into membrane interactions has uncovered a diverse range of therapeutic opportunities through the bioengineering of human and non-human macromolecules. Although the majority of this research is focussed on fundamental developments, emerging studies are showcasing promising new techno...
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| Veröffentlicht in: | Archives of biochemistry and biophysics 2024-05, Vol.755, p.109939, Article 109939 |
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| container_title | Archives of biochemistry and biophysics |
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| creator | Upton, Calum Healey, Joseph Rothnie, Alice J. Goddard, Alan D. |
| description | Recent research into membrane interactions has uncovered a diverse range of therapeutic opportunities through the bioengineering of human and non-human macromolecules.
Although the majority of this research is focussed on fundamental developments, emerging studies are showcasing promising new technologies to combat conditions such as cancer, Alzheimer's and inflammatory and immune-based disease, utilising the alteration of bacteriophage, adenovirus, bacterial toxins, type 6 secretion systems, annexins, mitochondrial antiviral signalling proteins and bacterial nano-syringes. To advance the field further, each of these opportunities need to be better understood, and the therapeutic models need to be further optimised.
Here, we summarise the knowledge and insights into several membrane interactions and detail their current and potential uses therapeutically.
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| doi_str_mv | 10.1016/j.abb.2024.109939 |
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Although the majority of this research is focussed on fundamental developments, emerging studies are showcasing promising new technologies to combat conditions such as cancer, Alzheimer's and inflammatory and immune-based disease, utilising the alteration of bacteriophage, adenovirus, bacterial toxins, type 6 secretion systems, annexins, mitochondrial antiviral signalling proteins and bacterial nano-syringes. To advance the field further, each of these opportunities need to be better understood, and the therapeutic models need to be further optimised.
Here, we summarise the knowledge and insights into several membrane interactions and detail their current and potential uses therapeutically.
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Although the majority of this research is focussed on fundamental developments, emerging studies are showcasing promising new technologies to combat conditions such as cancer, Alzheimer's and inflammatory and immune-based disease, utilising the alteration of bacteriophage, adenovirus, bacterial toxins, type 6 secretion systems, annexins, mitochondrial antiviral signalling proteins and bacterial nano-syringes. To advance the field further, each of these opportunities need to be better understood, and the therapeutic models need to be further optimised.
Here, we summarise the knowledge and insights into several membrane interactions and detail their current and potential uses therapeutically.
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Although the majority of this research is focussed on fundamental developments, emerging studies are showcasing promising new technologies to combat conditions such as cancer, Alzheimer's and inflammatory and immune-based disease, utilising the alteration of bacteriophage, adenovirus, bacterial toxins, type 6 secretion systems, annexins, mitochondrial antiviral signalling proteins and bacterial nano-syringes. To advance the field further, each of these opportunities need to be better understood, and the therapeutic models need to be further optimised.
Here, we summarise the knowledge and insights into several membrane interactions and detail their current and potential uses therapeutically.
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| source | Elsevier ScienceDirect Journals |
| subjects | Adenoviridae Adenovirus Alzheimer disease Bacteriophage T4 bacteriophages biochemistry biophysics Biotechnology humans Membrane interactions mitochondria Photorhabdus virulence cassette therapeutics |
| title | Insights into membrane interactions and their therapeutic potential |
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