Vascular protein disulfide isomerase A1 mediates endothelial dysfunction induced by angiotensin II in mice

Aim Protein disulfide isomerases (PDIs) are involved in platelet aggregation and intravascular thrombosis, but their role in regulating endothelial function is unclear. Here, we characterized the involvement of vascular PDIA1 in angiotensin II (Ang II)‐induced endothelial dysfunction in mice. Method...

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Veröffentlicht in:	Acta Physiologica 2024-04, Vol.240 (4), p.e14116-n/a
Hauptverfasser:	Kij, Agnieszka, Bar, Anna, Czyzynska‐Cichon, Izabela, Przyborowski, Kamil, Proniewski, Bartosz, Mateuszuk, Lukasz, Kurylowicz, Zuzanna, Jasztal, Agnieszka, Buczek, Elzbieta, Kurpinska, Anna, Suraj‐Prazmowska, Joanna, Marczyk, Brygida, Matyjaszczyk‐Gwarda, Karolina, Daiber, Andreas, Oelze, Matthias, Walczak, Maria, Chlopicki, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	AIM protein Angiotensin Angiotensin II Antithrombin Aorta bepristat Bioavailability Coronary vessels Electron spin resonance endothelial dysfunction Magnetic resonance imaging Nitric oxide Nitrogen dioxide Oxidative stress PDIA1 Platelet aggregation Protein disulfide-isomerase Thrombin Thrombosis Vasodilation
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