Strategies for Improving Impaired Osseointegration in Compromised Animal Models

Implant osseointegration is reduced in patients with systemic conditions that compromise bone quality, such as osteoporosis, disuse syndrome, and type 2 diabetes. Studies using rodent models designed to mimic these compromised conditions demonstrated reduced bone-to-implant contact (BIC) or a declin...

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Veröffentlicht in:	Journal of Dental Research 2024-05, Vol.103 (5), p.467-476
Hauptverfasser:	Deng, J., Van Duyn, C., Cohen, D. J., Schwartz, Z., Boyan, B. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animal models Animals Bone growth Bone mineral density Bone resorption Bone-Implant Interface Cell differentiation Cell interactions Cell proliferation Dental Implantation, Endosseous Dental Implants Diabetes mellitus (non-insulin dependent) Disease Models, Animal Humans Immunomodulation Microenvironments Osseointegration Osseointegration - physiology Osteoblastogenesis Osteoblasts Osteoblasts - physiology Osteoclastogenesis Osteoclasts Osteogenesis Osteogenesis - physiology Osteoporosis Osteoprogenitor cells Stromal cells Surface Properties
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