SinoNasal Microbiota Transfer to treat recalcitrant chronic rhinosinusitis: A case series

Key points SinoNasal Microbiota Transfer (SNMT) was safe with immediate benefit in all recipients, with sustained improvement in two of three recipients for up to 180 days. The addition of antimicrobial photodynamic therapy worsened chronic rhinosinusitis. These promising SNMT results warrant furthe...

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Veröffentlicht in:	International forum of allergy & rhinology 2024-08, Vol.14 (8), p.1386-1390
Hauptverfasser:	Gill, Sandeep K., Hernaiz‐Leonardo, Juan C., Edens, Thaddeus J., Pascual, Athenea, Tang, Chris, Fan, Judy, Thamboo, Andrew, Mullings, Warren, Alsaleh, Saad, Alim, Bader M., Javer, Amin R., Manges, Amee R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Chronic Disease chronic rhinosinusitis experimental therapy Female Humans Male microbiome microbiome therapy Microbiota Middle Aged mucus transplant Paranasal Sinuses - microbiology Photodynamic therapy Rhinitis - microbiology Rhinitis - therapy Rhinosinusitis sinusitis Sinusitis - microbiology Sinusitis - therapy Treatment Outcome
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Zusammenfassung:	Key points SinoNasal Microbiota Transfer (SNMT) was safe with immediate benefit in all recipients, with sustained improvement in two of three recipients for up to 180 days. The addition of antimicrobial photodynamic therapy worsened chronic rhinosinusitis. These promising SNMT results warrant further study of safety and efficacy.
ISSN:	2042-6976 2042-6984 2042-6984
DOI:	10.1002/alr.23352