Current status of emergency medical service use in ST-segment elevation myocardial infarction in China: Findings from China Acute Myocardial Infarction (CAMI) Registry

The mortality rate of myocardial infarction in China has increased dramatically in the past three decades. Although emergency medical service (EMS) played a pivotal role for the management of patients with ST-segment elevation myocardial infarction (STEMI), the corresponding data in China are limite...

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Veröffentlicht in:International journal of cardiology 2024-07, Vol.406, p.132040, Article 132040
Hauptverfasser: Yang, Jingang, Zhao, Yanyan, Wang, Jianyi, Ma, Liyuan, Xu, Haiyan, Leng, Wenxiu, Wang, Yang, Wang, Yan, Wang, Zhifang, Gao, Xiaojin, Yang, Yuejin
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container_title International journal of cardiology
container_volume 406
creator Yang, Jingang
Zhao, Yanyan
Wang, Jianyi
Ma, Liyuan
Xu, Haiyan
Leng, Wenxiu
Wang, Yang
Wang, Yan
Wang, Zhifang
Gao, Xiaojin
Yang, Yuejin
description The mortality rate of myocardial infarction in China has increased dramatically in the past three decades. Although emergency medical service (EMS) played a pivotal role for the management of patients with ST-segment elevation myocardial infarction (STEMI), the corresponding data in China are limited. An observational analysis was performed in 26,305 STEMI patients, who were documented in China acute myocardial infarction (CAMI) Registry and treated in 162 hospitals from January 1st, 2013 to January 31th, 2016. We compared the differences such as demographic factors, social factors, medical history, risk factors, socioeconomic distribution and treatment strategies between EMS transport group and self-transport group. Only 4336 patients (16.5%) were transported by EMS. Patients with symptom onset outside, out-of-hospital cardiac arrest and presented to province-level hospital were more likely to use EMS. Besides those factors, low systolic blood pressure, severe dyspnea or syncope, and high Killip class were also positively related to EMS activation. Notably, compared to self-transport, use of EMS was associated with a shorter prehospital delay (median, 180 vs. 245 min, P 
doi_str_mv 10.1016/j.ijcard.2024.132040
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Although emergency medical service (EMS) played a pivotal role for the management of patients with ST-segment elevation myocardial infarction (STEMI), the corresponding data in China are limited. An observational analysis was performed in 26,305 STEMI patients, who were documented in China acute myocardial infarction (CAMI) Registry and treated in 162 hospitals from January 1st, 2013 to January 31th, 2016. We compared the differences such as demographic factors, social factors, medical history, risk factors, socioeconomic distribution and treatment strategies between EMS transport group and self-transport group. Only 4336 patients (16.5%) were transported by EMS. Patients with symptom onset outside, out-of-hospital cardiac arrest and presented to province-level hospital were more likely to use EMS. Besides those factors, low systolic blood pressure, severe dyspnea or syncope, and high Killip class were also positively related to EMS activation. Notably, compared to self-transport, use of EMS was associated with a shorter prehospital delay (median, 180 vs. 245 min, P &lt; 0.0001) but similar door-to-needle time (median, 45 min vs. 52 min, P = 0.1400) and door-to-balloon time (median, 105 min vs. 103 min, P = 0.1834). EMS care for STEMI is greatly underused in China. EMS transport is associated with shorter onset-to-door time and higher rate of reperfusion, but not substantial reduction in treatment delays or mortality rate. Targeted efforts are needed to promote EMS use when chest pain occurs and to set up a unique regionalized STEMI network focusing on integration of prehospital care procedures in China. Trial registration:ClinicalTrials.gov (NCT01874691), retrospectively registered June 11, 2013. •Only 16.5% of patients with ST-segment elevation myocardial infarction (STEMI) are transported by EMS in China.•Use of EMS is associated with shorter onset-to-door time and higher reperfusion rate among hospitalized STEMI patients.•Setting up a unique regionalized STEMI network focusing on shortening prehospital delay is a main challenge in China.</description><identifier>ISSN: 0167-5273</identifier><identifier>ISSN: 1874-1754</identifier><identifier>EISSN: 1874-1754</identifier><identifier>DOI: 10.1016/j.ijcard.2024.132040</identifier><identifier>PMID: 38614365</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Aged ; China - epidemiology ; Emergency medical service ; Emergency Medical Services - statistics &amp; numerical data ; Female ; Humans ; Male ; Middle Aged ; Registries ; Reperfusion therapy ; ST Elevation Myocardial Infarction - diagnosis ; ST Elevation Myocardial Infarction - epidemiology ; ST Elevation Myocardial Infarction - mortality ; ST Elevation Myocardial Infarction - therapy ; ST-segment elevation myocardial infarction ; Time-to-Treatment - trends</subject><ispartof>International journal of cardiology, 2024-07, Vol.406, p.132040, Article 132040</ispartof><rights>2024</rights><rights>Copyright © 2024. 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Zhao, Yanyan ; Wang, Jianyi ; Ma, Liyuan ; Xu, Haiyan ; Leng, Wenxiu ; Wang, Yang ; Wang, Yan ; Wang, Zhifang ; Gao, Xiaojin ; Yang, Yuejin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c311t-6719b2bea296d0a418b53fe3f0ed0fde2be301b19543ed6e31825293c27023a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Aged</topic><topic>China - epidemiology</topic><topic>Emergency medical service</topic><topic>Emergency Medical Services - statistics &amp; numerical data</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Registries</topic><topic>Reperfusion therapy</topic><topic>ST Elevation Myocardial Infarction - diagnosis</topic><topic>ST Elevation Myocardial Infarction - epidemiology</topic><topic>ST Elevation Myocardial Infarction - mortality</topic><topic>ST Elevation Myocardial Infarction - therapy</topic><topic>ST-segment elevation myocardial infarction</topic><topic>Time-to-Treatment - trends</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Jingang</creatorcontrib><creatorcontrib>Zhao, Yanyan</creatorcontrib><creatorcontrib>Wang, Jianyi</creatorcontrib><creatorcontrib>Ma, Liyuan</creatorcontrib><creatorcontrib>Xu, Haiyan</creatorcontrib><creatorcontrib>Leng, Wenxiu</creatorcontrib><creatorcontrib>Wang, Yang</creatorcontrib><creatorcontrib>Wang, Yan</creatorcontrib><creatorcontrib>Wang, Zhifang</creatorcontrib><creatorcontrib>Gao, Xiaojin</creatorcontrib><creatorcontrib>Yang, Yuejin</creatorcontrib><creatorcontrib>China Acute Myocardial Infarction Registry Research Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Jingang</au><au>Zhao, Yanyan</au><au>Wang, Jianyi</au><au>Ma, Liyuan</au><au>Xu, Haiyan</au><au>Leng, Wenxiu</au><au>Wang, Yang</au><au>Wang, Yan</au><au>Wang, Zhifang</au><au>Gao, Xiaojin</au><au>Yang, Yuejin</au><aucorp>China Acute Myocardial Infarction Registry Research Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Current status of emergency medical service use in ST-segment elevation myocardial infarction in China: Findings from China Acute Myocardial Infarction (CAMI) Registry</atitle><jtitle>International journal of cardiology</jtitle><addtitle>Int J Cardiol</addtitle><date>2024-07-01</date><risdate>2024</risdate><volume>406</volume><spage>132040</spage><pages>132040-</pages><artnum>132040</artnum><issn>0167-5273</issn><issn>1874-1754</issn><eissn>1874-1754</eissn><abstract>The mortality rate of myocardial infarction in China has increased dramatically in the past three decades. Although emergency medical service (EMS) played a pivotal role for the management of patients with ST-segment elevation myocardial infarction (STEMI), the corresponding data in China are limited. An observational analysis was performed in 26,305 STEMI patients, who were documented in China acute myocardial infarction (CAMI) Registry and treated in 162 hospitals from January 1st, 2013 to January 31th, 2016. We compared the differences such as demographic factors, social factors, medical history, risk factors, socioeconomic distribution and treatment strategies between EMS transport group and self-transport group. Only 4336 patients (16.5%) were transported by EMS. Patients with symptom onset outside, out-of-hospital cardiac arrest and presented to province-level hospital were more likely to use EMS. Besides those factors, low systolic blood pressure, severe dyspnea or syncope, and high Killip class were also positively related to EMS activation. Notably, compared to self-transport, use of EMS was associated with a shorter prehospital delay (median, 180 vs. 245 min, P &lt; 0.0001) but similar door-to-needle time (median, 45 min vs. 52 min, P = 0.1400) and door-to-balloon time (median, 105 min vs. 103 min, P = 0.1834). EMS care for STEMI is greatly underused in China. EMS transport is associated with shorter onset-to-door time and higher rate of reperfusion, but not substantial reduction in treatment delays or mortality rate. Targeted efforts are needed to promote EMS use when chest pain occurs and to set up a unique regionalized STEMI network focusing on integration of prehospital care procedures in China. Trial registration:ClinicalTrials.gov (NCT01874691), retrospectively registered June 11, 2013. •Only 16.5% of patients with ST-segment elevation myocardial infarction (STEMI) are transported by EMS in China.•Use of EMS is associated with shorter onset-to-door time and higher reperfusion rate among hospitalized STEMI patients.•Setting up a unique regionalized STEMI network focusing on shortening prehospital delay is a main challenge in China.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>38614365</pmid><doi>10.1016/j.ijcard.2024.132040</doi></addata></record>
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subjects Aged
China - epidemiology
Emergency medical service
Emergency Medical Services - statistics & numerical data
Female
Humans
Male
Middle Aged
Registries
Reperfusion therapy
ST Elevation Myocardial Infarction - diagnosis
ST Elevation Myocardial Infarction - epidemiology
ST Elevation Myocardial Infarction - mortality
ST Elevation Myocardial Infarction - therapy
ST-segment elevation myocardial infarction
Time-to-Treatment - trends
title Current status of emergency medical service use in ST-segment elevation myocardial infarction in China: Findings from China Acute Myocardial Infarction (CAMI) Registry
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