Map conformational landscapes of intrinsically disordered proteins with polymer physics quantities

Disordered proteins are conformationally flexible proteins that are biologically important and have been implicated in devastating diseases such as Alzheimer’s disease and cancer. Unlike stably folded structured proteins, disordered proteins sample a range of different conformations that needs to be...

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Veröffentlicht in:	Biophysical journal 2024-05, Vol.123 (10), p.1253-1263
Hauptverfasser:	Shadman, Hossain, Ziebarth, Jesse D., Gallops, Caleb E., Luo, Ray, Li, Zhengxin, Chen, Hai-Feng, Wang, Yongmei
Format:	Artikel
Sprache:	eng
Schlagworte:	Intrinsically Disordered Proteins - chemistry Models, Molecular Polymers - chemistry Protein Conformation
Online-Zugang:	Volltext
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