Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg Effect

Advanced urothelial bladder cancer (UBC) patients are tagged by a dismal prognosis and high mortality rates, mostly due to their poor response to standard-of-care platinum-based therapy. Mediators of chemoresistance are not fully elucidated. This work aimed to study the metabolic profile of advanced...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancers 2024-04, Vol.16 (7), p.1418
Hauptverfasser:	Afonso, Julieta, Barbosa-Matos, Catarina, Silvestre, Ricardo, Pereira-Vieira, Joana, Gonçalves, Samuel Martins, Mendes-Alves, Camille, Parpot, Pier, Pinto, Joana, Carapito, Ângela, Guedes de Pinho, Paula, Santos, Lúcio, Longatto-Filho, Adhemar, Baltazar, Fátima
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidification Amino acids Antibodies Biomarkers Biosynthesis Bladder cancer California Cancer therapies Cell cycle Cell growth Chemoresistance Cisplatin Dehydrogenases Genotype & phenotype Glucose Glucose metabolism Glutamate Glycolysis Health aspects Japan Kinases Laboratories Lactates Lactic acid Lipid metabolism Massachusetts Medical prognosis Medical research Medicine, Experimental Metabolic pathways Metabolism Metabolomics Metastasis Missouri Mitochondrial DNA Mortality Older people Oxidative phosphorylation Oxygen consumption Phenotypes Phosphorylation Physiological aspects Portugal Proteins Scientific equipment and supplies industry Tumors United States Urothelial cancer
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!